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Alaka`ina Foundation Family of Companies · 1 month ago

Senior Biomarker Repository Technician

Frederick, MD

Full-time

Onsite

Senior Level

The Alaka`ina Foundation Family of Companies is a fast-growing government service provider seeking a Senior Biomarker Repository Technician. The role involves executing protocols for biomarker verification, conducting experiments in BSL-2, BSL-3, and BSL-4 environments, and managing a biosample repository for biomarker evaluation.

CharityCommunitiesGovernment

No H1B

U.S. Citizen Only

Responsibilities

Assist in the development of and independently execute protocols adhering to the experimental design for biomarker verification as determined in collaboration with the respective project Lead/PI in a BSL-2, BSL-3, and BSL-4 environment

Perform experiments at BSL-2, BSL-3, and BSL-4 as required by the experimental design and respective organisms

Perform next generation sequencing, Nanostring immunological and inflammatory panels, Luminex-based platforms, miRNA quantification, as well as other molecular diagnostic techniques

Conduct experiments for detection of etiologic agents within animal and clinical samples

Perform laboratory work requiring expertise in small animal handling with associative trainings completed

Assist the Lead/PIs in preparation of technical reports and manuscripts for publication

Perform laboratory work required to fulfil experimental designs for novel sample collection/concentration/processing to include Nanotrap Concentration, and DNA/mRNA purification from both NHP and Human clinical matrices

Present protocols and data generated at weekly meetings as requested

Utilize biomarker expertise to identify unexpected or invalid results. Communicate and troubleshoot assay and instrument issues with the respective project Lead/PI

Perform experiments at BSL-2, BSL-3 and/or BSL-4 as required by the experimental design and respective organisms

CONUS/OCONUS travel may be required in support of the diagnostic mission and/or presentation of scientific research

Work with appropriate Lead/PIs to establish and maintain responsibility of a biosample repository for biomarker evaluation and verification

Perform highly detailed clinical sample testing in support of priority BSL-2, BSL-3, and/or BSL-4 animal studies or human clinical sample surveillance studies

Train new laboratory members in BSL-2, BSL-3, and/or BSL-4 project-specific laboratory techniques and methods

Serve as the laboratory supervisor for assigned laboratory spaces to ensure the laboratory meets required safety, functionality, and stocking requirements

Consolidate and analyze biomarker data and repository metadata in support of technical reports, presentations, and manuscripts

Facilitate the planning, preparation, and laboratory research execution support of approximately 5-8 projects per year

Contribute to a Biomarker Quarter and Annual Reports for associate projects

Contribute to the collection, management, and analysis of Biomarker Data for assigned projects

Author, review and revise Biomarker SOPs as required to support assigned projects

Other duties as assigned by Supervisor

Qualification

Next-generation sequencingMolecular techniquesBSL-2 laboratory experienceCell cultureInfectious agents handlingData analysisTraining laboratory membersTechnical report preparation

Required

Master's Degree in a Biological Science

Experience with cell culture and handling of biological samples

Proficiency in a range of molecular techniques: Next-generation sequencing (NGS) library preparation and data analysis, Nanostring assays, Luminex multiplex assays, PCR (including RT-PCR and qPCR), miRNA quantification, and nucleic acid purification

Experience working in BSL-2 and ideally BSL-3 laboratories. Experience in BSL-4 would be a significant advantage

Experience in handling infectious agents and complex assays

U.S. Citizen

BPRP enrollment required

Must pass NACI background check