insitro · 1 week ago
Sr / Staff Software Engineer, Imaging
South San Francisco, CA
Full-time
Hybrid
Senior Level, Lead/Staff
$185K/yr - $235K/yr
6+ years expinsitro is an ML-driven biotech company tackling the grand challenge of drug discovery. They are seeking an experienced Senior Software Engineer to join their Imaging Software Team, responsible for building platform features that integrate novel imaging modalities and machine learning into drug discovery workflows.
BiotechnologyHealth CareLife ScienceMachine LearningPharmaceuticalTherapeutics
Responsibilities
Platform Enablement: Partner with lab and ML scientists to design, develop, and scale platform capabilities required to design, run, and interpret ML-powered high-content screens
Production Hardening: Scale and harden complex image processing and ML workflows, taking them from research prototype to reliable, routine use
User Tooling: Build and evolve robust tools and interactive interfaces for data exploration, quality assessment, and visualization to help scientists iterate quickly on experimental data
Collaboration: Collaborate closely with lab scientists, ML scientists, and microscopy teams to translate complex experimental needs into clear, actionable technical plans and high-quality, shipped software
Data Integrity: Set and uphold best-in-class practices for data integrity, lineage, reproducibility, and observability across the entire imaging data lifecycle
Qualification
Required
6+ years of professional experience building and operating production-grade software and high-throughput data pipelines, primarily using Python
Proven ability to own complex, end-to-end projects, making thoughtful architectural trade-offs, and delivering solutions incrementally with a focus on long-term maintainability
Thrive in cross-functional settings and excel at translating abstract research and experimental needs into practical, scalable software systems
Enjoy sharing knowledge, mentoring others, and are capable of writing clear, exemplary technical specifications and documentation
Preferred
Direct experience designing, building, and deploying machine learning pipelines, visualizations, and QC processes for large-scale imaging or similar high-dimensional datasets
Prior experience working with large biological datasets and/or high-content imaging is beneficial
Familiarity with our core Python-first ML stack, distributed compute technologies (e.g., PyTorch/Lightning, Ray, Kubernetes), and workflow orchestration tools (e.g., Argo, Airflow, or redun)
Benefits
401(k) plan with employer matching for contributions
Excellent medical, dental, and vision coverage as well as mental health and well-being support
Open, flexible vacation policy
Paid parental leave of at least 16 weeks to support parents who give birth, and 10 weeks for a new parent (inclusive of birth, adoption, fostering, etc)
Quarterly budget for books and online courses for self-development
Support to attend professional conferences that are meaningful to your career growth and role's responsibilities
New hire stipend for home office setup
Monthly cell phone & internet stipend
Access to free onsite baristas and cafe with daily lunch and breakfast for employees who are either onsite or hybrid
Access to free onsite fitness center for employees who are either onsite or hybrid
Access to a free commuter bus and ferry network that provides transport to and from our South San Francisco HQ from locations all around the Bay Area
Company
insitro
Insitro is a drug discovery and development startup that utilizes machine learning and biology to transform drug discovery.
201-500 employees
H1B Sponsorship
insitro has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (12)
2023 (12)
2022 (7)
2021 (4)
2020 (8)
Funding
Current Stage
Growth StageTotal Funding
$643MKey Investors
CPP InvestmentsAndreessen Horowitz
2021-03-15Series C· $400M
2020-05-26Series B· $143M
2018-05-02Series A· $100M
Leadership Team
Daphne Koller
Founder and CEO
D
Divya Kanichar
Director
Recent News
2026-01-06
Company data provided by crunchbase