Hughes and Associates · 1 month ago
Executive Director, Head of Pharmacometrics
Massachusetts, United States
Full-time
Onsite
Director/Executive
10+ years expHughes and Associates is seeking an Executive Director to lead pharmacometrics activities, overseeing modeling and simulation across clinical programs. The role involves shaping quantitative strategies for study design and regulatory interactions, requiring deep scientific expertise and operational leadership.
Staffing & Recruiting
Responsibilities
Define and execute pharmacometric strategies to support dose optimization, clinical trial design, and decision-making throughout the drug development lifecycle
Provide translational insight by connecting preclinical findings to clinical application in novel disease areas
Drive collaboration across clinical development, biometrics, regulatory affairs, and translational science teams
Guide the development of mechanistic and empirical models (e.g., PK/PD, QSP) to enable key milestones, including proof-of-concept and registrational studies
Lead, mentor, and manage a team of pharmacometricians
Oversee authorship and review of pharmacometric components of regulatory submissions and support agency engagement
Remain current with scientific advances and integrate innovative approaches to enhance modeling capabilities
Qualification
Required
Ph.D. in Clinical Pharmacology, Pharmacometrics, or related field
10+ years of industry experience in quantitative clinical development
Expertise in PK/PD, QSP, and modeling software (e.g., R, NONMEM, MATLAB)
Strong leadership, regulatory, and cross-functional collaboration experience
Company
Hughes and Associates
🔬 HUGHES AND ASSOCIATES Executive & Technical Search for the Pharmaceutical and Biotechnology Industries At Hughes and Associates, we’re more than recruiters — we’re strategic partners in advancing careers and building world-class teams across the life sciences industry.
2-10 employees
Funding
Current Stage
Early StageCompany data provided by crunchbase