Manus · 2 months ago
Computational Research Scientist, Enzyme Engineering
Waltham, MA
Full-time
Onsite
Mid, Senior LevelManus is a company focused on accelerating the transition to BioAlternatives through sustainable solutions. They are seeking a Computational Research Scientist specialized in deep learning to tackle enzyme engineering challenges, contributing to AI tool development for better enzymes and bioprocesses.
BiopharmaBiotechnologyFood and Beverage
Responsibilities
Develop predictive models for enzyme engineering using machine-learning/deep-learning techniques
Leverage in-house enzyme engineering data to enhance machine-learning/deep-learning models
Develop and implement computational approaches using 3D structures and/or sequences as input to increase enzyme stability, solubility and activity
Assist with maintenance of hardware and software to support computational bioengineering Perform protein variant designs with established protocols to support in-house projects
Collaborate with experimental biologists to design and interpret experiments that validate computational predictions
Communicate results and insights to multidisciplinary teams, including presentations and written reports
Qualification
Required
Ph.D. in Bioengineering, Biochemistry, Biostatistics, Chemical Engineering, Computer Science, or similar discipline, ideally with a focus on AI driven techniques and deep learning
Proven experience with deep learning frameworks (e.g., TensorFlow, PyTorch) and libraries
Proficiency in programming languages such as Python, R, or MATLAB
Experience using computational tools to improve enzyme activity and/or specificity
Excellent communication skills, both written and verbal
Preferred
Knowledge of protein structural modeling and prediction
Experience in industrial biotechnology or a related industry
Experience building and optimizing deep learning architectures, transformers and diffusion-based models
Background in enzyme catalysis and reaction mechanisms
Must be very well-organized and be able to handle multiple projects simultaneously
Must be a quick learner who is self-motivated and able to ask questions and seek clarity
Must be flexible with day-to-day duties and able to thrive in a start-up environment
Must be an excellent team member with strong communication skills and a desire to work collaboratively
Must hold themselves to the highest professional, scientific and ethical standards
Company
Manus
Manus is the world’s leading bioalternatives scale-up platform.
Founded in 2011
51-200 employees
H1B Sponsorship
Manus has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
2022 (2)
2021 (1)
2020 (2)
Funding
Current Stage
Growth StageTotal Funding
$131.07MKey Investors
U.S. Department of Health & Human ServicesBill & Melinda Gates FoundationBBGI
2024-11-26Grant· $32.4M
2022-08-31Grant· $2M
2020-11-17Series B· $75M
Leadership Team
Ajikumar Parayil
Founder and CEO
Christine Santos
Chief Technology Officer
Recent News
Labiotech UG
2025-09-04
2025-04-09
Company data provided by crunchbase