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Variantyx · 3 months ago

Clinical NGS Laboratory Technician

Framingham, MA

Full-time

Onsite

Entry, Mid Level

2+ years exp

Variantyx is a technology-driven precision medicine company providing state-of-the-art diagnostic solutions for rare genetic disorders and oncology treatment optimization. The Clinical NGS Laboratory Technician performs high complexity laboratory testing on patient specimens and ensures compliance with quality control and assurance procedures.

BiotechnologyGeneticsHealth CareHealth DiagnosticsLife Science

Responsibilities

Processing specimens for high complexity testing using automated systems and/or manual procedures in accordance with the laboratory’s standard operating procedures (SOPs)

Accession samples in LIMS

Next Generation Sequencing (NGS) with other sequencing and assay platforms

Some of the processes: DNA isolation – Manual and Automated, Generate NGS libraries, Manual and Automated, PCR amplification

NGS using Illumina NovaSeq6000 and Nanopore PromethION platforms, data analysis, tissue, and cell culture

Maintain strict standards of quality

Assist in general upkeep of the laboratory

Maintain laboratory supplies and inventory

Write, review, and maintain SOPs and Policies

Participate in quality control and quality assurance activities

Maintain laboratory equipment and instruments according to SOPs

Participate in continuing education

Other duties as assigned by the Laboratory Supervisor

Qualification

Next Generation SequencingIllumina sequencing platformsMolecular biology techniquesQuality control proceduresLaboratory equipment proficiencyComputer literacyCommunication skillsOrganizational skills

Required

A BSc, MSc in life sciences/Biology/Molecular Biology/Biochemistry or related field

Experience with NGS techniques is required

Minimum 2-year experience in a high complexity molecular diagnostic laboratory

Experience with and understanding of general laboratory equipment

Basic understanding of human genetics and biology of DNA/RNA

Proficiency in molecular biology techniques

Excellent written and oral communication skills

Must possess excellent computer literacy skills (Google and/or Microsoft suites, spreadsheet calculations)

Able to organize, prioritize, and delegate tasks to efficiently move projects forward

Preferred

Qualifications compatible with Massachusetts and/or New York CLIA General Supervisor classification (per CFR § 493.1461 ) are desirable but not required

Experience with the Illumina sequencing platforms is highly desirable

Understanding of NGS data and metrics is highly desirable

Experience working with automated liquid handlers is highly desirable