Eli Lilly and Company · 7 hours ago
Advisor/Senior Advisor, Purification Development - Bioconjugates
Indianapolis, IN
Full-time
Onsite
Mid, Senior Level
$126K/yr - $205K/yr
5+ years expEli Lilly and Company is a global healthcare leader dedicated to improving lives through the discovery and delivery of innovative medicines. The role of Advisor/Senior Advisor in Purification Development focuses on developing new purification technologies and optimizing downstream processes for biologic candidates, particularly bioconjugates, while ensuring adherence to safety and environmental guidelines.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Identify and develop new purification technologies
Design optimized downstream drug substance processes for new biologic candidates with particular focus on complex bioconjugates
Maintain accurate records and interpret data to provide detailed information and analysis on the execution of experiments
Employ strategic thinking to overcome technical hurdles and oversee process and technical transfer to GMP manufacturing facilities, as they make their way from discovery to the clinic
Write technical reports, tech transfer documents and give presentations to summarize development activities
Have flexibility to accept new projects and challenges
Troubleshoot issues as they occur and identify trends and opportunities to reduce process variability
Qualification
Required
PhD in Chemical Engineering or related degree focused on biological separation sciences OR
MS in Chemistry, Chemical Engineering, or related degree with at least 5 years relevant experience in leading protein purification/process development OR
BS in Chemistry, Chemical Engineering, or related degree with at least 8 years relevant experience in leading protein purification/process development
Hands-on experience with bioconjugate purification
Preferred
Ability to exhibit a high level of attention to detail, a quality-minded approach to experimental design and record keeping
Effective oral and written communication skills
Strong laboratory skills
Experience developing, optimizing, scaling, and tech transferring conjugation reactions for mAbs or other proteins (e.g., PEGylation, ADCs, antibody-oligonucleotide conjugates)
Experience with bioconjugate purification challenges including maintaining conjugate stability, optimizing conjugation ratios, and separating conjugated from unconjugated species
Understanding of conjugation chemistry mechanisms and their impact on downstream purification strategies (e.g., hydrophobic interaction chromatography or anion exchange chromatography for conjugate separation)
Purification development experience with AAV, mRNA, or other gene therapy strategies
Ability to interact and form dynamic relationships with a wide range of groups
Experience with process control and documentation systems (Unicorn, Empower, electronic laboratory notebooks)
General interpersonal and communication skills; mentoring, feedback, training, and cultivating an environment for learning and open/honest communication
Basic analytical skills and understanding
Advanced problem-solving skills
Benefits
Company bonus (depending, in part, on company and individual performance)
Eligibility to participate in a company-sponsored 401(k)
Pension
Vacation benefits
Eligibility for medical, dental, vision and prescription drug benefits
Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
Life insurance and death benefits
Certain time off and leave of absence benefits
Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Company
Eli Lilly and Company
We're a medicine company turning science into healing to make life better for people around the world.
10001+ employees
H1B Sponsorship
Eli Lilly and Company has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (514)
2024 (236)
2023 (167)
2022 (133)
2021 (57)
2020 (52)
Funding
Current Stage
Public CompanyTotal Funding
$6.5M2024-02-12Post Ipo Debt· $6.5M
1978-01-13IPO
Leadership Team
David Ricks
Chair, CEO
Lucas Montarce
Executive Vice President and Chief Financial Officer
Recent News
2025-12-30
2025-12-30
Company data provided by crunchbase