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TRexBio · 4 weeks ago

Senior Scientist, Bioanalytical, Pharmacokinetics, and Immunology Assays

South San Francisco, CA

Full-time

Onsite

Mid, Senior Level

$130K/yr - $160K/yr

3+ years exp

TRexBio is a clinical stage biotechnology company focused on developing revolutionary therapeutics for inflammatory diseases. The Senior Scientist will be responsible for assay development and optimization, collaborating with cross-functional teams to support preclinical programs and contributing to the advancement of the therapeutic pipeline.

BioinformaticsBiopharmaBiotechnology

Responsibilities

Design, develop, and execute assays to support PK/PD package of preclinical programs

Develop and optimize bioanalytical assays to quantify therapeutic proteins and biomarkers (e.g., ELISA, MSD)

Apply immunological techniques (e.g., flow cytometry, multiplex cytokine profiling) to characterize surface markers and immune cell states

Interpret and present data to cross-functional teams, contributing to dose-response and exposure–response modeling

Collaborate closely with discovery biology, in vivo pharmacology, and computational groups to advance pipeline candidates

Provide subject matter expertise in assay design, validation, and troubleshooting

Mentor junior scientists and contribute to team growth and best practices

Maintain detailed records in compliance with industry standards; support preparation of data packages for internal reviews and external partners

Qualification

Bioanalytical assay developmentImmunoassay platformsFlow cytometryData analysisRegulatory assay validationCollaborationMentoring

Required

PhD in Immunology, Pharmacology, Biochemistry, or a related discipline with 3+ years of postdoctoral or industry experience; OR MS with 7+ years of biotech/pharma experience

Demonstrated expertise in bioanalytical assay development for therapeutic proteins

Strong technical proficiency in across immunoassay platforms and immune profiling techniques (e.g., ELISA, MSD, and flow cytometry)

Familiarity with immune cell surface marker analysis and characterization

Strong data analysis skills with the ability to communicate findings clearly across disciplines

Proven ability to work effectively in collaborative, fast-paced environments

Preferred

Experience with regulatory assay validation (GLP/GCLP) desirable but not required

Benefits

Discretionary Bonus

Company

TRexBio

TRexBio is a clinical-stage biotechnology company discovering and developing immunoregulatory medicines based on tissue Treg biology by leveraging cutting-edge computational biology tools, a focus on human tissue, and deep immunobiology expertise.

Founded in 2018

South San Francisco, California, USA

11-50 employees