Charles R. Drew University of Medicine and Science · 1 month ago
Senior Research Technologist (Mass Spectrometry & Proteomics)
Charles R. Drew University of Medicine and Science is a mission-driven institution focused on providing equitable healthcare resources. They are seeking a Senior Research Technologist to provide advanced scientific and technical expertise in mass spectrometry-based proteomics, overseeing laboratory operations and contributing to research initiatives.
Higher Education
Responsibilities
Develops standard operating protocols and manages overall function for CDU research labs and Core labs
Implement a new laboratory management system (Agilent iLab) for all specialized equipment, see equipment list below
Design, plan, and independently conduct proteomics and mass spectrometry experiments, including protein/peptide preparation, quantitative proteomics (e.g., SILAC, TMT, iTRAQ), and targeted or discovery-based workflows
Develop and optimize new methodologies for protein/peptide separation, enrichment, and analysis
Collaborate with PIs and investigators to shape experimental design and align proteomic approaches with research objectives
Operate, maintain, and oversee mass spectrometry platforms (e.g., Orbitrap, timsTOF, Q-TOF, ion-trap) and associated LC systems
Lead the development and implementation of SOPs for proteomics workflows
Monitor system performance, conduct troubleshooting, and ensure rigorous quality control
Analyze and interpret proteomics datasets, collaborating with bioinformatics teams to ensure robust data pipelines
Contribute to manuscripts, presentations, and grant proposals with high-level scientific input
Serve as an institutional resource for proteomics expertise, fostering cross-disciplinary collaborations
Train and mentor junior scientists, technicians, students, and postdocs in proteomics methods and mass spectrometry operation
Provide guidance on study design, experimental troubleshooting, and data analysis strategies
Promote a collaborative, team-based research culture
Supervise daily proteomics operations, including scheduling of instrument time, reagent management, and vendor interactions
Ensure compliance with safety, biosafety, and chemical handling regulations
Implement a new laboratory management system (Agilent iLab) for all specialized equipment, see equipment list below
Develop a business model for Laboratory Research Operation
Develop external user contacts for the core Services
Availability to work on weekends and evenings to complete time-sensitive projects
Oversee Laboratory staff, including research assistants and technicians
Work with CDU Facility management, security, and departments
Qualification
Required
PhD in Chemistry, Biochemistry, Proteomics, or a related field with 2+ years of postdoctoral or industry experience, OR
Master's degree with 5+ years of proteomics/mass spectrometry experience, OR
Bachelor's degree with 7+ years of advanced proteomics experience
Expertise in LC-MS/MS workflows for proteomics, including quantitative and label-free approaches
Proficiency with data analysis platforms (e.g., MaxQuant, Proteome Discoverer, Skyline, Spectronaut)
Familiarity with metabolomics, lipidomics, or multi-omics integration is desirable
Strong record of troubleshooting, innovation, and method development
Preferred
Demonstrated ability to lead and collaborate across diverse research teams
Strong scientific writing and presentation skills
Proven mentoring, leadership, and project management experience
Company
Charles R. Drew University of Medicine and Science
Charles R. Drew University of Medicine and Science (CDU) is a private, nonprofit, nonsectarian, medical and health sciences institution.
H1B Sponsorship
Charles R. Drew University of Medicine and Science has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2024 (3)
2023 (1)
2022 (4)
2021 (3)
2020 (4)
Funding
Current Stage
Late StageTotal Funding
$0.8MKey Investors
ConstellationThe California Endowment
2025-11-20Grant
2019-12-13Grant· $0.8M
Leadership Team
Recent News
2025-03-05
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