North Carolina State University · 2 months ago
Lead Research Scientist, Metabolomics
Triangle Area
Full-time
Onsite
Senior Level, Lead/Staff
$85K/yr - $108K/yr
5+ years expNorth Carolina State University is seeking a Lead Research Scientist in Metabolomics to support their Molecular Education, Technology and Research Innovation Center (METRIC). The role involves providing expert consultation on metabolomics, performing sample preparation and analysis, and collaborating with researchers to advance scientific projects.
EducationNon ProfitUniversities
Responsibilities
Serve as the point of contact for client inquiries in the area of small molecule analysis by targeted and untargeted metabolomics, including lipidomics
Provide expert advice on experimental design, including selection of sample preparation techniques and analytical methods, to ensure methodological rigor and feasibility
Collaborate with other staff members to develop and optimize metabolomics experimental protocols
Stay abreast of the latest advances in analytical methods and techniques to integrate into research projects
Perform liquid, liquid-liquid, or SPE extraction, derivatization, and other pre-analytical steps to ensure sample integrity and suitability for downstream analysis
Operate and maintain LC-MS metabolomics instrumentation (e.g. Thermo TSQ Altis Triple Quadrupole, Exploris 240, Exploris 480, ID-X)
Develop and implement standard operating procedures (SOPs) for sample handling and preparation to ensure consistency across studies
Perform metabolomics studies and report the results (analyte peak area or concentrations) using relevant software such as Skyline, MS-Dial, and Compound Discoverer
Use appropriate statistical and bioinformatics tools to extract meaningful biological insights
Perform pathway analysis using specialized software and databases, as needed
Interpret complex datasets and collaborate with researchers to contextualize findings within the scope of the project
Prepare detailed reports and visualizations of data for internal review, publication in scientific journals, and use in grant applications
Maintain accurate and up-to-date laboratory records, including experimental protocols, data logs, and inventory of samples and reagents
Coordinate with the operations manager to ensure adequate supplies; ensure continuity of operations by coordinating maintenance of major instrumentation and associated ancillary equipment
Assist in the training and supervision of staff and students in metabolomics techniques and best practices
Contribute to the preparation of manuscripts, grant applications, and progress reports for funding agencies
Ensure compliance with institutional and regulatory requirements related to biosafety, data management, and ethical standards
Qualification
Required
Ph.D. in a relevant field, with at least five years of experience in metabolomics research methods and/or post-degree professional work experience with a demonstrated record of research achievement
Relevant Master's degree, plus at least 8 years of exceptional relevant professional work experience and a record of research achievements
In rare instances, an individual with comparable professional experience but less than a master's degree will be considered, on an exception basis. May require terminal degree and licensure
Significant experience in untargeted and targeted metabolomics, advanced separations, tandem MS, absolute quantification, IROA, credentialing, bioinformatics, and metabolome databases
Demonstrated ability to develop workflows and standard operating procedures (SOPs)
Must possess exceptional communication skills, including written and verbal, be highly organized and detail-oriented
Must be able to work independently, use initiative, prioritize tasks, and anticipate potential pressure points in workflows
Ability to develop and maintain productive collaborative work relationships with all clients by listening, understanding and responding to apparent and underlying needs and continually seeking to provide the highest quality service to all
Preferred
Prefer experience with lipidomics and/or mass spectrometry-based imaging
Prefer experience with integrating data from multiple-omics based approaches
Benefits
Medical , Dental , and Vision
Flexible Spending Account
Retirement Programs
Disability Plans
Life Insurance
Accident Plan
Paid Time Off and Other Leave Programs
12 Holidays Each Year
Tuition and Academic Assistance
Childcare benefits
Wellness & Recreation Membership
Wellness Programs
Company
North Carolina State University
North Carolina State University is an educational institution that offers graduate and undergraduate programs.
10001+ employees
H1B Sponsorship
North Carolina State University has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (211)
2024 (134)
2023 (164)
2022 (106)
2021 (90)
2020 (108)
Funding
Current Stage
Late StageTotal Funding
$60.84MKey Investors
National Institute of Food and AgricultureNational Safety CouncilBezos Earth Fund
2024-06-26Grant· $0.27M
2024-06-13Grant· $0.05M
2024-05-31Grant· $30M
Leadership Team
Marshall Brain
Director
Recent News
2026-01-06
Maryland Daily Record
2025-12-21
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