Synthesize Bio · 2 months ago
Principal AI Researcher
Washington, United States
Full-time
Onsite
Lead/Staff
$170K/yr - $250K/yrSynthesize Bio is an early stage startup focused on using generative AI to transform life sciences research and accelerate biomedical discovery. The Principal AI Researcher will lead generative AI research projects, develop models for experimental biology data, and provide mentorship to junior team members while shaping the technical vision of the AI/ML program.
Biotechnology
No H1B
Responsibilities
Lead the technical execution of key generative AI research projects
Develop, train, and deploy foundational generative models for experimental biology data into production
Help shape the AI/ML program's long-term technical vision
Provide technical guidance and mentorship to junior team members, including on other technical teams (e.g. software devs and computational biologists)
Lead innovative efforts in applying recent developments in the AI/ML literature to develop models that accelerate drug development
Successfully build and deploy generative foundation models for experimental biology
Actively contribute to technical vision and roadmap development
Set technical standards for model training, MLOps, and deployment in the cloud
Proactively collaborate with other teams to integrate AI models into the broader platform
Qualification
Required
Experience with developing AI/ML models to advance drug development or clinical research
Knowledge of NGS data (pre-clinical genomic or transcriptomic) or proteomic data
Experience training AI/ML models with AWS, Microsoft Azure, or Google Cloud Platform
Development experience with PyTorch, Tensorflow, JAX, or similar
Knowledge of key MLOps, including model training, hosted inference options, and batch/stream processing
Experience deploying AI/ML models in production environments
Proven track record of successfully developing AI/ML models in a relevant domain (e.g. biomedicine, life science, healthcare)
Demonstrated ability to lead technical projects, implement state-of-the-art research (e.g., generative models/diffusion/transformers), and deliver measurable results in a technically rigorous environment
Experience contributing to the technical vision and roadmap of an AI product or platform
Experience publishing in the AI/ML literature and implementing/developing new methodology based on research ideas
Preferred
Experience fine-tuning and prompting Large Language Models
Experience managing model experimentation, development, and evaluation
Building models that are relevant to highly technical scientific domains
Understanding of or interest in computational genomics and applications of AI to biology
Benefits
100% employer paid health insurance premiums, 50% dependents
401k plan access (non-matching)
Gym access for Seattle-based employees
Company
Synthesize Bio
Synthesize Bio uses AI to reduce data collection and analysis for a fraction of the cost in time, personnel, and materials.
Founded in 2023
11-50 employees
Funding
Current Stage
Early StageTotal Funding
$10MKey Investors
Madrona
2025-09-16Seed· $10M
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