Abzena · 3 weeks ago
Process Development Associate I, Downstream
San Diego, CA
Full-time
Onsite
Entry Level
$60K/yr - $70K/yr
1+ years expAbzena is a company dedicated to developing biologics and bioconjugates, ensuring quality excellence in getting vital medicines to patients. The Process Development Associate I will perform process development activities, collaborating with various departments to create scalable and robust processes while maintaining compliance with regulatory requirements.
BiopharmaBiotechnologyLife SciencePharmaceutical
Responsibilities
Executes experiments in protein recovery and purification process development using column chromatography and various other techniques
Assists with technical transfer of downstream purification processes from clients and between Process Development and other internal groups like Cell Line Development and MSAT/MFG
Assists in scale-up calculations for varying scales of the process — up to cGMP scale
Calculates buffer formulations correctly and makes buffers accurately according to protocols
Assists in the documentation of observations and collecting data for analysis. Capable of data management. Capable of identifying trends in data and notifying scientists of possible impacts
Conducts activities in support of production schedules and objectives as directed by senior staff
Maintains detailed records to comply with regulatory requirements and assists with in-process testing
Maintains lab organization and cleanliness by regularly stocking supplies, scheduled cleanings, and managing supply inventory
Assembles and autoclaves tubing assemblies
Maintains cleanliness of specific equipment such as AKTA systems and biosafety cabinets
Maintains up-to-date knowledge of quantitative and qualitative analytical methods
Represents Process Development and its activities, as needed, during project team meetings, training, and evaluation of new technologies
As needed, assists with protein purification under cGMP standards for production of clinical trial material
Operates to the highest ethical and moral standards
Complies with Abzena's policies and procedures
Communicates effectively with clients, supervisors, colleagues and staff
Participates effectively as a team player in all aspects of Abzena's business
Adheres to quality standards set by regulations and Abzena policies, procedures, and mission
Performs other duties as assigned
Qualification
Required
Minimum BS degree in biological sciences, chemistry, chemical engineering, biotechnology, biochemistry or related fields
1-3 years experience in pharmaceutical or biotechnology field
Basic knowledge of recombinant protein expression and protein purification strategies using various chromatographic techniques
Basic knowledge in protein chemistry and analytical methods
Basic understanding and hands-on experience with AKTA systems and Unicorn software: GE- Pure, Avant, Pilot, and Ready
Basic understanding of centrifugation, depth filtration and TFF
Knowledge of buffer formulation and preparation
Comfortable in a fast-paced environment with minimal direction and able to adjust workload based upon changing priorities
Skilled with Microsoft Office suite
Ability to follow detailed instructions and to maintain accurate records and notes
Ability to work effectively in a team environment and motivated to work on multiple and various tasks, when required
Skilled in problem solving and troubleshooting
Ability to safely operate production equipment in accordance with established practices
Company
Abzena
Abzena is a biotechnology company that offers biologic and ADC products from concept to clinic.
501-1000 employees
H1B Sponsorship
Abzena has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$139.44MKey Investors
Biospring PartnersProVen VCT
2022-03-31Private Equity· $65M
2020-07-28Private Equity· $10M
2018-08-16Acquired
Leadership Team
Geoffrey Glass
Chief Executive Officer
Daniel Giroux
Vice President, Development
Recent News
Genetic Engineering News
2025-11-08
2025-10-24
Company data provided by crunchbase