Kernal Biologics · 2 months ago
Sr. Scientist/ Scientist, Antibody Development & Production
Boston, MA
Full-time
Onsite
Mid, Senior Level
2+ years expKernal Bio is a venture-backed therapeutics company engineering cells inside the body using AI-designed technologies. They are seeking a highly motivated scientist for antibody development and production to lead the design, development, and production of novel antibodies for targeted LNP applications and establish internal capabilities to support preclinical research.
BiotechnologyPharmaceuticalTherapeutics
Responsibilities
Lead antibody development and production activities at external collaborators (e.g., CROs, CDMOs) for preclinical research activities as well as GMP production
Responsible for reviewing and approving critical documentation (e.g., protocols, process development batch records, analytical methods, specifications, etc)
Establish internal capabilities for the development, production, and analysis of antibody supplies to accelerate and troubleshoot external development activities and provide materials for preclinical research
Review, supervise, and/or execute experiments to optimize cell culture, harvest, and downstream purification
Author tech transfer documentation (e.g., process descriptions, bill of materials, draft specifications, analytical methods) based on both external collaborator activities and internal development activities
Maintain thorough and detailed electronic laboratory notebooks
Analyze, interpret, and summarize experimental data
Communicate results to team and management in technical reports and oral presentations
Qualification
Required
Degree in Chemical/Biomedical Engineering, Pharmaceutical Sciences, Biochemistry, Analytical Chemistry or a similar field
B.S (or equivalent) with 4-6 years of experience, M.S (or equivalent) with 2-4 years of experience, or PhD with 0-2 years of experience
Experience with the development and/or production of recombinant proteins, monoclonal antibodies, and/or antibody fragments
Experience in mammalian cell culture and transfection
Experience with harvest and purification technologies (e.g., normal flow filtration, tangential flow filtration, chromatography, virus filtration)
Experience using Design of Experiments (DOE) to optimize cell culture yields/titers and/or performance of downstream purification
Familiar with analytical methods commonly used for antibody assays (e.g., SEC, WB, ELISA, SDS-PAGE, etc)
Strong molecular biology skills
Ability to analyze, summarize, and communicate scientific data
Attention to detail, ability to multitask, and troubleshoot
Strong written and verbal communication skills
Excellent record-keeping and data management skills
Experience working in fast-paced startup environments
Ability to work independently while effectively interacting and collaborating in a team environment
Adaptability and enthusiasm for new challenges, innate curiosity, and a passion for learning
Preferred
Experience with difficult-to-produce proteins/protein fragments (e.g., low titer or low solubility)
Experience with plasmid vector design and codon engineering (nice to have)
Benefits
Competitive 401(k)
Highly competitive healthcare coverage (PPO/HMO)
Free parking, a monthly subway pass, or a subsidized commuter rail pass
Free Bluebike Membership
Gym Membership Support
Flexible Spending Account
Paid parental leave, family caregiver leave, and medical leave
Paid life insurance coverage
On-site cafeteria
Competitive vacation and sick days per year
Company
Kernal Biologics
Kernalbio creates mRNA therapies that instruct specific cells on how to make their own medicine.
11-50 employees
H1B Sponsorship
Kernal Biologics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (2)
2021 (1)
Funding
Current Stage
Early StageTotal Funding
$73MKey Investors
Advanced Research Projects Agency for HealthHummingbird Ventures
2025-10-07Grant· $48M
2022-07-07Series A· $25M
2020-10-21Seed
Leadership Team
B
Burak Yilmaz
Founder & President
Recent News
Google Patent
2025-02-08
Company data provided by crunchbase