Senior Scientist – Bioprocess Development jobs in United States
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Ecolab · 2 days ago

Senior Scientist – Bioprocess Development

Ecolab is seeking a passionate and experienced Senior Scientist to lead downstream process development efforts focused on the chromatographic purification of monoclonal antibodies (mAbs). This role involves guiding a small team in designing and executing purification strategies while collaborating with external biopharma clients to advance their molecules toward commercialization.

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H1B Sponsor Likelynote

Responsibilities

Design, execute, and analyze chromatography-based purification processes (Protein A, ion exchange, HIC, etc.) for mAbs
Develop scalable, robust purification processes tailored to client molecules and manufacturing goals
Lead technology transfer activities to external manufacturing sites
Author technical reports, protocols, and support regulatory documentation
Collaborate directly with major biopharma clients to align on study design, timelines, and deliverables
Deliver high-quality experimental results that support their development pipelines and regulatory submissions
Serve as a trusted scientific partner, helping clients overcome technical challenges and accelerate their path to market
Oversee day-to-day lab operations, including equipment maintenance, inventory, and safety compliance
Mentor and guide junior scientists and research associates
Foster a culture of scientific rigor, operational discipline, and continuous improvement

Qualification

ChromatographyAntibody purificationDownstream process developmentAKTA systemsHPLCCGMP/cGLP standardsTeam leadershipTechnical writingCommunication skillsProblem-solving skills

Required

M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8 years of relevant industry experience, or Ph.D. with 5 years of experience in downstream process development for biologics
Demonstrated expertise in preparative chromatography and antibody purification
Proven ability to lead small scientific teams and manage lab operations

Preferred

Hands-on experience with AKTA systems, Unicorn software, and high-throughput screening platforms (e.g., Tecan Te-Chrom)
Proficiency in analytical techniques such as HPLC, SDS-PAGE, ELISA, UV spectroscopy
Familiarity with tech transfer, cGMP/cGLP standards, and regulatory documentation
Experience in client-facing or CDMO environments is a plus
Strong communication, organizational, and problem-solving skills
Working knowledge of statistical tools (e.g., JMP,) and data analysis software

Benefits

Ecolab strives to provide comprehensive and market-competitive benefits to meet the needs of our associates and their families.

Company

Ecolab provides water, hygiene and infection prevention solutions and services that protect people and the resources vital to life. It is a sub-organization of Ecolab Life Sciences.

H1B Sponsorship

Ecolab has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (34)
2024 (37)
2023 (31)
2022 (31)
2021 (49)
2020 (42)

Funding

Current Stage
Public Company
Total Funding
unknown
1978-01-13IPO

Leadership Team

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Christophe Beck
Chairman and CEO at Ecolab
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Daniel Schmechel
Chief Financial Officer
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