Mass General Brigham · 4 weeks ago
Project Lead Biologics, Amplify
Somerville, MA
Full-time
Onsite
Senior Level, Lead/Staff
$144K/yr - $210K/yr
10+ years expMass General Brigham is a not-for-profit organization that supports patient care, research, teaching, and community service. The Project Lead, Biologics is responsible for leading technology projects within the Amplify portfolio, focusing on translating promising ideas into reality and creating value with new technologies.
Health CareHome Health CareMedical
Responsibilities
Leads assigned as well as invested projects in close collaboration with the Amplify leadership team, physicians and researchers at the hospitals, Innovation colleagues, and industry representatives
The Project Lead Amplify will in effect perform as the principal of chief science/operational officer for their portfolio projects
Applies knowledge of biologic therapeutic product development to effectively diligence, select, scope, plan/budget, pitch, and implement early innovative projects of their own, as well as assist in other project triage and diligences as part of the Amplify team
Can readily assess commercial potential of assigned projects and assess the key risks to be mitigated
Has a working understanding of intellectual property filing and prosecution, especially as it intersects with new company or partnership commercialization strategies
Effectively conducts direct and regular interactions with hospital-based investigators and stakeholders, investors and industry collaborators, external advisors, contract vendors and consultants
Runs the day-to-day science operations of multiple projects in collaboration with Mass General Brigham researchers, with oversight of external contract vendors and consultants engaged in activities that may include discovery to candidate nomination of biologic molecules, safety studies, product manufacturing, development of clinical and regulatory plans, and commercial analyses
Effective in designing product/program plans to individual experiments, including analyzing and interpreting in vitro and in vivo datasets
Capable of developing and managing program budgets and engaging with finance and operations colleagues to oversee spending, as well as inform commercialization plans
Ensures that deliverables associated with each project is completed on time, within budget to meet or exceed targets set by Amplify
Capable of producing high quality written materials for project operations, communications with stakeholders, and pitches for project approval to internal and external investment committees
Thrives in working in close collaboration with colleagues working in diverse roles, including other Amplify Leads, MGB Ventures, MGB academic Innovators, BD & Licensing, and other MGB Translational Program Managers
In addition to their Amplify responsibilities, the Project Lead will also serve as an experienced advisory resource to Venture and Licensing colleagues, as well as other Innovation colleagues engaged in translational development and initiatives for Mass General Brigham technologies
Qualification
Required
Advanced degree(s) in science/technology/engineering plus 5-10+ years of increasing responsibility in project management
Experience in industry-based drug product development environment of 10+ years is required
Prior experience in diligencing technologies either internally at a company or as a consultant to companies or investors
Expertise with product development of biologic therapeutics including antibodies, ADCs, enzymes, recombinant fusion proteins, vaccines
Familiarity with technologies and platforms used to develop biologic therapeutics including immunization, library screening, in silico and structural design, as well as production of research grade to GMP proteins, plasmids, and cell lines
Deep and demonstrated experience with immunology and/or cell biology
Strong ability to connect fundamental target biology to drug mechanisms
Extensive capability across a wide range of technologies in assay development
Proficiency in Microsoft Office applications as well as project management tools
Strong ability to manage competing complex deliverables and deadlines
Demonstrates exceptional verbal, writing, presentation skills
Specific expertise with biologic drug development of monoclonal antibodies, recombinant enzymes and other proteins, vaccines, is essential
Experience in overseeing IND-enabling activities including non-clinical pharmacology and CMC, and advancing programs to the IND stage or beyond is beneficial
Preferred
Experience in successfully fundraising and operating in a startup environment is a plus
Established network of drug development contacts as well as investors is preferred
Enthusiasm for working with exceptional and innovative researchers and technologies
Benefits
Comprehensive benefits
Career advancement opportunities
Differentials
Premiums and bonuses as applicable
Recognition programs designed to celebrate your contributions and support your professional growth
Company
Mass General Brigham
Mass General Brigham specializes in providing medical treatments and health diagnostics services.
10001+ employees
H1B Sponsorship
Mass General Brigham has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (77)
2024 (61)
2023 (93)
2022 (70)
2021 (80)
2020 (29)
Funding
Current Stage
Late StageLeadership Team
E
Erin Flanigan
SVP, Human Resources, Community, Specialty Hospital Division
O’Neil A. Britton
Chief Integration Officer, Executive Vice President
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