Twist Bioscience · 1 day ago
Instrument Software Engineer
South San Francisco, CA
Full-time
Onsite
Mid, Senior Level
$139K/yr - $155K/yr
3+ years expTwist Bioscience is a company focused on synthesizing genes from scratch, contributing to advancements in various fields including health care and agriculture. They are seeking an Instrument Software Engineer to design and develop software for laboratory instruments, interface with manufacturing systems, and provide technical support while ensuring software reliability and compliance.
B2BBiotechnologyChemicalHealth CareLife Science
Responsibilities
Design, implement, and maintain software that controls and communicates with laboratory instruments
Develop user interfaces, data acquisition modules, hardware abstraction layers, and real-time control logic
Sustain and troubleshoot existing instrument software used in production environments
Collaborate with hardware, electrical, mechanical, and systems engineers to ensure seamless integration between software and hardware components
Develop and support communication protocols (e.g., USB, RS-232, CAN, TCP/IP) for instrument control and data exchange
Provide ongoing software support for deployed instruments, especially in manufacturing and lab environments
Investigate and resolve bugs, performance issues, and integration failures in collaboration with the support and testing teams
Work with test engineers to develop and execute verification and validation protocols to ensure software reliability and compliance
Support automated and manual testing of instrument software, including regression testing
Write and maintain detailed technical documentation, including design specifications, software architecture, and user manuals
Ensure software complies with applicable regulatory standards (e.g., FDA, ISO 13485, if applicable)
Contribute to research and development efforts for next-generation instruments
Evaluate new technologies, frameworks, and methodologies to improve instrument performance and usability
Work closely with scientists, lab personnel, manufacturing teams, and field service engineers to gather feedback and implement improvements
Participate in design reviews and product development meetings to align software solutions with business and user needs
Qualification
Required
BS in Computer Science or a related field plus 5 years of relevant experience or Master's degree in Computer Science or related field plus 3 years of relevant experience
Proficient in C#, WPF, and UX
Extensive background with electro-mechanical systems and instrumentation
Familiar with Agile and software development lifecycle
Good understanding of software design principles
Knowledgeable in scientific computation and data analysis
Hands-on experience with lab instrumentation and integrated systems
Excellent communication and writing skills, and ability to work in a fast-paced team environment
Experience with LIMS (Laboratory Information Management System) and MES (Manufacturing Execution System) is a strong plus
Preferred
MVVM experience
Experience with Visual Studio, Git, Jira, and Azure is nice to have
Benefits
Bonus
Equity
Generous benefits package
Company
Twist Bioscience
Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries.
501-1000 employees
H1B Sponsorship
Twist Bioscience has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (18)
2024 (14)
2023 (22)
2022 (19)
2021 (4)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$553.11MKey Investors
Capital World InvestorsBiomatics Capital PartnersIllumina
2022-02-09Post Ipo Equity· $250M
2020-01-27Post Ipo Equity· $50M
2018-10-30IPO
Leadership Team
Emily Leproust
CEO
Siyuan Chen
Chief Technology Officer
Recent News
2026-01-07
2025-12-30
Company data provided by crunchbase