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Iambic Therapeutics · 2 months ago

Research Scientist II, High Throughput Chemistry

San Diego HQ

Full-time

Onsite

Mid, Senior Level

$123K/yr - $154K/yr

2+ years exp

Iambic Therapeutics is a clinical-stage life-science and technology company focused on developing novel medicines using AI-driven discovery. The Research Scientist II will design and execute high-throughput experiments, collaborate across multiple teams, and optimize synthetic methodologies to advance compound library campaigns.

Artificial Intelligence (AI)Machine LearningSoftwareTherapeutics

Responsibilities

Design and execute parallel synthetic methods to generate large, high-quality compound libraries

Identify, develop, and optimize novel synthetic methodologies with a focus on automation compatibility and HTE scalability

Apply newly developed synthetic routes from traditional bench-scale chemistry to robust, high-throughput, and automated processes

Oversee the operation, maintenance, and continuous advancement of our chemistry toolkit and automated synthesis equipment

Analyze research outcomes and library compound data and clearly communicate results and findings to cross-functional project teams

Ensure all laboratory work is conducted in accordance with established safety protocols and best laboratory and ELN data recording practices

A strong commitment to teamwork and the ability to function effectively as a core member of an interdisciplinary scientific team (chemistry, biology, software, and automation)

Proactive problem-solving mindset leveraging attention to detail and available resources to identifying bottlenecks, troubleshooting automated processes, and developing solutions to ensure business continuity

Qualification

Organic ChemistryHigh Throughput ChemistryLaboratory AutomationParallel SynthesisMedicinal ChemistryTeamworkProblem-solvingCommunication SkillsMentoring

Required

Ph.D. degree in Organic Chemistry with 2-5 years of industry experience or Master of Science (MS) degree in Organic Chemistry with 8+ years of industry experience in synthetic organic chemistry

Strong command of modern organic synthetic methods

Direct hands-on experience with High Throughput Chemistry and/or Parallel Synthesis

Experience with laboratory automation, liquid handling robotics, and automated analytical and purification systems

Ability to thrive in fast-paced, highly collaborative, and dynamic research environment

Excellent written and verbal communication skills; must be able to articulate complex scientific concepts, technical challenges, and results clearly and concisely to diverse audiences

Proven ability to thrive in a fast-paced, high-volume environment where priorities and synthetic targets may shift rapidly based on biological data