Scientist I, Clinical Biomarker Development (Cancer Genomics) jobs in United States
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Revolution Medicines · 1 day ago

Scientist I, Clinical Biomarker Development (Cancer Genomics)

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The Cancer Genomics Scientist I will apply advanced analytics and genomics solutions to clinical biomarker data, collaborate with cross-functional teams, and communicate findings to various audiences.

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H1B Sponsor Likelynote

Responsibilities

Apply advanced analytics and genomics solutions to clinical biomarker data to inform research & development, including machine learning methods with high throughput NGS genomic data
Integrate multi-omics datasets (e.g. spatial transcriptomics, liquid biopsy, and other NGS approaches) to interrogate disease biology, resistance mechanisms, and predict drug response
Collaborate with cross functional teams, managing interactions with key stakeholders to deliver robust biomarker analyses and recommend follow up actions
Communicate results to expert and non-expert audiences, including internal cross-functional team members and external collaborators, through scientific publications and presentations

Qualification

Ph.D. in Cancer GenomicsR programmingPython programmingNGS data analysisLinux proficiencyCloud computingRNAseq data analysisGenomics workflowsAI/ML approachesData-driven inquiryCommunication skillsInterpersonal skills

Required

A Ph.D. in Cancer Genomics, Genetics, Computational Biology, or similar degree in which cancer biology is integrated with genomics data analysis
Proficiency programming in R and/or Python for computational biology analysis
Expert in clearly documenting work with a version control system (git)
Experienced in Linux and the cloud, including HPC clusters and command line interface
Practiced at developing genomics workflows for large scale NGS datasets
Expert in the interrogation of RNAseq data, such as bulk, single-cell, and spatial transcriptomics data, preferably including utilization of single-cell atlas data to inform analysis flow
Experienced working with DNA sequence data (mutation, liquid biopsy, CGP, WES, or similar)
Practiced in commonly used tools and methods (Seurat, Scanpy, GATK, Bioconductor, etc) and in utilizing publicly available datasets (TCGA, cBioPortal) to interrogate cancer genomics data
Strong interpersonal, verbal and written communication skills; proactive, self-motivated, and adaptable in a dynamic environment
Demonstrated ability to translate complex data into clear biological insight, and to influence project direction through data-driven scientific inquiry

Preferred

Experienced with AI/ML approaches to integrate single-cell & spatial transcriptomics data
Deep knowledge of pancreatic cancer, preferably including how progression, response and resistance may be mediated by tumor microenvironment and/or transcriptional programming
Trained in cancer signaling biology with strong understanding of RAS/MAPK signaling pathways
Strong understanding of statistics and the ability to generate robust predictive models for outcomes in multidimensional data

Benefits

Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities

Company

Revolution Medicines

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Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.

H1B Sponsorship

Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)

Funding

Current Stage
Public Company
Total Funding
$2.25B
Key Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M

Leadership Team

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Luan Wilfong
Chief Human Resources Officer
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Steve Kelsey
President
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Company data provided by crunchbase