Revolution Medicines · 2 months ago
Senior Scientist I, Protein Biochemistry/Enzymology
Redwood City, California, United States
Full-time
Onsite
Senior Level
$144K/yr - $180K/yr
5+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The role involves designing and applying biochemical assays, performing kinetic studies, and contributing to drug discovery efforts in oncology.
Health CareLife ScienceMedical
Responsibilities
Design, develop, and apply biochemical assays to functionally characterize proteins, understand their role in oncology, and enable hit finding and validation efforts
Perform kinetic studies to support a deep understanding of small molecules with complex mechanisms of action, including covalent and non-covalent molecular glue inhibitors and activators
Contribute to early discovery efforts to validate novel oncology targets and therapeutic modalities
Support cross-functional teams to generate novel insights and drive drug discovery and development
Effectively communicate findings to diverse audiences through presentations, reports, and publications
Qualification
Required
Ph.D. in Biochemistry, Enzymology, Chemical Biology, or a related field with 5-8 years of experience, preferably in an industrial setting
Thorough understanding of enzyme kinetics and the ability to design, analyze, and interpret experimental results
Hands-on experience handling recombinant proteins and analyzing activity through experimental assays (fluorescence, absorbance, luminescence, FRET, mass spectrometry, etc.)
Rigorous and detail-oriented approach to data analysis and interpretation
Knowledge of protein structure-function interpretation and proficiency with software to visualize protein structures
Strong analytical and problem-solving skills with the ability to work independently
Excellent written and verbal communication skills, including the ability to communicate complex concepts to a variety of audiences
Preferred
Experience in target ID and hit ID stage programs in biotech
Proficient with software to model multi-step enzyme reactions (DynaFit, SimBiology, PySB, etc.)
Familiarity with modern laboratory automation, data systems, and analytics and ability to design experiments to take advantage of these systems
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
2026-01-11
The Motley Fool
2026-01-11
Company data provided by crunchbase