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BIOQUAL · 1 day ago

Senior Scientist

Rockville, MD

Full-time

Onsite

Senior Level, Lead/Staff

$60/hr - $75/hr

8+ years exp

BIOQUAL is a research-focused company seeking a Senior Scientist to oversee various aspects of experimental protocols and client interactions. The role involves managing projects, developing assays, and advancing research programs through scientific expertise and collaboration.

Test and Measurement

Responsibilities

Design, develop, and validate complex vitro assays, including 3D organoid models, to evaluate drug efficacy and toxicity

Collaborate cross-functionally with internal teams to integrate in vitro findings into broader preclinical studies and ensure timely delivery of projects, maintain quality standards and meeting tight deadlines

Engage directly with sponsors to understand their specific needs, providing tailored assay solutions and ensuring high levels of client satisfaction

Manage multiple projects simultaneously and adapt to evolving priorities in a fast- paced environment

Implement high-throughput screening (HTS) methodologies to facilitate large-scale compound testing, as applicable

Lead the expansion and optimization of in vitro assay offerings in alignment with evolving market demands and sponsor requirements

Stay abreast of industry trends and technological advancements to inform strategic decisions and maintain a competitive edge in assay development services

Maintain accurate and detailed experimental records and contribute to technical reports and publications

Qualification

3D organoid culture techniquesHigh-throughput screening assaysData analysis softwareAutomated liquid handling systemsRegulatory complianceCommitment to emerging technologiesExperience in CROProblem-solving skillsCommunication skillsCollaborative skills

Required

Ph.D. Cell Biology, Molecular Biology, Pharmacology, Immunology or related field with a 8+ years of relevant experience, or M.S with 15+ years of experience

Proven expertise in 3D organoid culture techniques, including patient-derived organoids and microphysiological systems

Strong background in developing and executing high-throughput in vitro assays

Proficiency in data analysis software and electronic lab notebooks

Excellent problem-solving skills and the ability to work independently and collaboratively in a fast-paced environment

Strong written and verbal communication skills for presenting data and authoring technical reports

Demonstrated ability to work collaboratively with interdisciplinary teams

Commitment to staying current with emerging technologies and methodologies in assay development and screening

Proven experience in designing, optimizing, and executing high-throughput screening assays for lead molecule discovery and early-stage drug development

Experience with automated liquid handling systems and high-content imaging platforms

Familiarity with regulatory requirements for preclinical assay validation

Statistical Design of Experiments (DoE): Knowledge of experimental design principles to optimize assay conditions and ensure robustness

Regulatory Compliance: Understanding of GLP practices and experience in preparing documentation for regulatory

Experience in a CRO or industry-based research setting