Monte Rosa Therapeutics · 2 months ago
Senior Research Associate I/II – In Vivo
Boston, MA
Full-time
Onsite
Mid, Senior Level
4+ years expMonte Rosa Therapeutics is searching for a Senior Research Associate I/II – In Vivo to assist in executing pivotal proof-of-concept studies in pre-clinical models in mice of inflammation, immunology, and oncology. The role involves designing and executing in vivo/ex vivo pharmacology studies and overseeing animal care and dosing as part of study protocols.
BiotechnologyMedicalTherapeutics
Responsibilities
Assist in executing pivotal proof-of-concept studies in pre-clinical models in mice of inflammation, immunology, and oncology
Interact with team members to design and execute in vivo/ex vivo pharmacology studies aimed at defining the activity and mechanism of action of compounds
Work primarily in the Animal Care Facility to oversee and perform afternoon/evening and weekend dosing of animals as part of study protocols
Perform basic and intermediate veterinary technical tasks in mice independently, including administration of selected agents by PO, IP, SC routes
Blood sampling techniques via multiple routes, including submandibular bleed
Carry out tissue harvests at later time points based on study requirements
Preparation of compound formulation for in vivo dosing
Optimize and perform studies to define target biology in mouse models of inflammation, oncology and immunity for in vivo, in vitro and ex vivo applications
Maintain accurate laboratory records/notebooks, procedures, and data summaries
Conduct health checks to ensure animal welfare and identify any concerns
Oversee breeding programs, including monitoring litters and documenting outcomes
Assist with cage changes and husbandry tasks as needed
Processing time-sensitive biological samples
Qualification
Required
BS/MS in Biology, Pharmacology, Animal Science, or related field with minimum 4 years relevant experience in an industry setting
Ability to work flexible hours, including evenings and weekends as needed, is a must
Prior experience necessary in handling compounds for formulation preparation, with a strong emphasis on safety and proficiency in performing necessary calculations
Strong experience in animal handling is required, including compound administration by multiple routes, harvesting tissue and blood samples, and performing necropsy techniques
Strong organizational skills and attention to detail
Willingness to learn new benchwork skills, including sample processing and cell culture
Preferred
AALAS certification at the ALAT level is preferred
LVT qualification is a plus
Experience in culturing mammalian cell lines is advantageous
Experience with pharmacodynamics assays of mouse tissue, including Western Blotting or JESS, ELISA/Mesoscale and flow cytometry is a plus, but not required
Experience with surgical techniques is a plus
Company
Monte Rosa Therapeutics
Monte Rosa Therapeutics is a biotechnology company that develops cancer therapeutics that modulate protein degradation pathways.
51-200 employees
H1B Sponsorship
Monte Rosa Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (1)
2022 (4)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$648.5MKey Investors
Avoro Capital AdvisorsAisling Capital
2026-01-08Post Ipo Equity· $300M
2024-05-15Post Ipo Equity· $100M
2023-10-26Post Ipo Equity· $25M
Leadership Team
S
Sharon Townson
Chief Scientific Officer
Recent News
2026-01-09
BioWorld Financial Watch
2026-01-09
2026-01-08
Company data provided by crunchbase