Biohub · 23 hours ago
Research Associate, Multiomics and Immune Profiling Lab
New York, NY
Full-time
Onsite
Entry, Mid Level
$71K/yr - $98K/yr
1+ years expBiohub is leading the new era of AI-powered biology to cure or prevent disease through its 501c3 medical research organization. They are seeking a skilled and collaborative Research Associate to support the development and operation of a Multiomics and Immune Profiling Lab at Yale University, focusing on immunology, flow cytometry, and cell-based assays.
BioinformaticsBiotechnologyGenetics
Responsibilities
Maintain and operate cell sorter and spectral flow cytometers
Manage human samples; coordinate sample processing and experimental workflows with collaborating investigators
Design and execute complex spectral flow cytometry experiments, including multi-parameter panel optimization and data acquisition
Set up and optimize in vitro cell stimulation assays and functional immunological readouts
Establish and maintain primary cell culture systems and immortalized cell lines for immunological studies
Develop and implement standardized protocols for cell-based assays, including viability assessment, proliferation assays, and cytokine measurements
PBMC isolation and processing
Perform quality control analysis of flow cytometry and immunological assay data to support experimental troubleshooting
Maintain detailed documentation of protocols, experimental conditions, and results
Work closely with other team members to support large-scale profiling and human immune monitoring projects
Contribute to the training and mentoring of junior team members on cell and flow cytometry techniques
Interacts with collaborators/PIs and their lab members to discuss and evaluate results
Interacts with external contacts such as staff at biotechnology and reagent companies to consult on and further develop research methods
Interact with EHS (environment, health, safety) officers to ensure the smooth and safe operation of the laboratory
Qualification
Required
Bachelor's or Master's degree in immunology, cell biology, molecular biology or a related field
Background in immunology with hands-on experience in immunological assays (e.g., ELISA, cytokine measurements, immune cell functional assays.)
1 year of experience with mammalian cell culture, including primary immune cells (e.g., T cells, B cells, monocytes, dendritic cells.)
Flow cytometry and cell sorting skills, including panel design, instrument operation, compensation, and data analysis (including using FlowJo.)
Experience with in vitro cell stimulation assays and functional readouts
Strong organizational skills and attention to detail in executing multi-step experimental workflows
Excellent communication skills and demonstrated ability to work collaboratively in team-based research environments
Enthusiasm for technology implementation and large-scale project execution and coordination rather than independent hypothesis-driven research
Preferred
3+ years of relevant research experience, or PhD in a relevant field with a keen interest in performing hands-on work in team settings
Experience with high-throughput or automated cell culture systems
Familiarity with additional flow cytometry techniques (e.g., imaging flow cytometry.)
Knowledge of cell-based screening platforms and plate-based assay formats
Experience working in core facility or technology platform settings
Basic programming skills (Python and/or R) for data processing and visualization
Benefits
Provides a generous employer match on employee 401(k) contributions to support planning for the future.
Paid time off to volunteer at an organization of your choice.
Funding for select family-forming benefits.
Relocation support for employees who need assistance moving
Company
Biohub
Our mission is to help scientists cure or prevent all disease.
201-500 employees
Funding
Current Stage
Growth StageLeadership Team
Rafael Gómez-Sjöberg
Chief Technology Officer
Eunitz Beganovic
Executive Assistant to the Chief Legal Officer
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