Centessa Pharmaceuticals · 2 days ago
Senior Director, Clinical Development
United States
Full-time
Hybrid
Lead/Staff, Director/Executive
$235K/yr - $310K/yr
5+ years expCentessa Pharmaceuticals is a new kind of pharmaceutical company focused on data-driven decision making and advancing a portfolio of programs with strong biological validation. The Senior Director, Clinical Development will lead the development of sleep-wake disorders and other CNS indications, collaborating with cross-functional teams and engaging with external partners to support clinical trials and regulatory submissions.
BiotechnologyPharmaceutical
Responsibilities
Author clinical study protocols for orexin agonists
Provide scientific and medical expertise to effectively execute clinical studies and advance accelerated development programs
Contribute to/develop the design of a cross-functionally aligned clinical development plan to advance multiple orexin agonist candidate molecules
Collaborate with clinical operations to meet timeline, cost and quality performance expectations and achieve program milestones
Provide medical insight and leadership in the design of translational medicine approaches exploring indication expansion opportunities
Effectively communicate and collaborate across internal disciplines and with key external partners/experts/investigators to position orexin agonist programs at the forefront of research and development for new medicines in sleep disorders
Provide oversight of study integrity and timelines, and communication of information pertaining to safety and efficacy of clinical candidate molecules
Author/ review clinical sections of regulatory documents, clinical study reports, scientific publications and presentations, and other program documents
Ensure adherence to Good Clinical Practices, pharmacovigilance standards, standard operating procedures and quality standards in conducting clinical research
Qualification
Required
MD in neurology or psychiatry (board certification preferred)
Clinical and/or academic experience in neurological disorders; and 5 years of pharmaceutical industry experience
Translational medicine expertise highly desired
Experience in early clinical development through late stage with successful design and implementation of proof-of-concept studies; submission experience in the neuroscience area is desired
Knowledge of US and EU regulatory guidelines and experience in interactions with regulatory agencies
Outstanding written and verbal communication, with a passion for problem solving and effective cross-functional stakeholder engagement
Ability to work independently and thrive in a fast-paced dynamic matrix environment
An entrepreneurial spirit with high degree of energy and personal accountability
Benefits
Discretionary annual bonus
Participation in our equity program
401(k) plan
Company-sponsored medical, dental, vision, and life insurance
Generous paid time off
Health and wellness program
Company
Centessa Pharmaceuticals
Centessa Pharmaceuticals is a next-generation biopharmaceutical company that aims to reshape the traditional drug development process.
51-200 employees
H1B Sponsorship
Centessa Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.12BKey Investors
Oberland Capital
2025-11-11Post Ipo Equity· $250M
2024-09-11Post Ipo Equity· $225M
2024-04-23Post Ipo Equity· $100M
Leadership Team
John Crowley
Chief Financial Officer
Gregory Weinhoff
Chief Business Officer
Recent News
2026-01-05
2025-12-14
Company data provided by crunchbase