The Jackson Laboratory · 20 hours ago
Associate Study Director, Gene Editing, Rare Disease Translational Center
Bar Harbor, ME
Full-time
Onsite
Mid, Senior Level
$75K/yr - $116K/yrThe Jackson Laboratory is an independent, nonprofit biomedical research institution focused on genomic solutions for disease. They are seeking a Scientist to support gene editing strategies for neurological disorders and rare diseases, managing research assistants and conducting various laboratory experiments.
BiotechnologyGeneticsHealth CareMedicalProduct Research
Responsibilities
End-to-end innovation and accountability: independently design, execute, optimize, and troubleshoot gene editing experiments to screen/identify lead gRNA candidates
Evaluate editing efficiency and specificity: design and conduct advanced NGS assays to assess On-Target and Off-Targets gene editing efficiency
Cell culture: culture and deliver CRISPR reagents in multiple formats (e.g. DNA, RNPs, lentivirus) to various cell types, including disease relevant cells (e.g. patient fibroblasts, iPSCs, etc). Differentiate cells into relevant cell types, mostly neuronal
Microbiology: clone gRNAs, epegRNAs, and gene fragments into plasmids, perform endotoxin-free preps, purify in vitro-transcribed RNAs
Molecular biology: purify biomolecules (DNA, RNA, and protein) from different sources (cells and tissue) using manual and/or automated technologies to support downstream biomolecular analyses using various techniques (e.g. NGS, qRT-PCR, ddPCR, western blot, flow cytometry, confocal microscopy, etc)
Other key attributes include: attention to detail, resourceful problem-solving, effective collaboration and communication
Qualification
Required
Bachelors degree required; Masters and PhD degree in Genetics, Biochemistry, Molecular Biology or related field, and extensive experience in cell biology preferred
Demonstrated ability to lead, direct, train and mentor teams required
Positive attitude and professional manner in all interactions; demonstrated commitment to continuous learning and professional development
Demonstrated ability to support staff to thrive on change and keep pace with a fast paced, dynamic work environment which is externally focused
Evidence of strong scientific productivity that would be demonstrated by publication in high-quality peer-reviewed journals
Ability to work with people across departments and gain their cooperation and commitment to projects with demanding deadlines
Excellent written and oral communication skills
Excellent organizational skills to track multiple inputs and maintain current drafts, arrange appropriate reviews, bring project to close in a timely manner to meet deadlines
Company
The Jackson Laboratory
The Jackson Laboratory conducts mammalian genetics research offering scientific services and resources to laboratories and students.
Founded in 1929
1001-5000 employees
H1B Sponsorship
The Jackson Laboratory has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (66)
2024 (50)
2023 (54)
2022 (55)
2021 (49)
2020 (38)
Funding
Current Stage
Late StageTotal Funding
$129.2MKey Investors
The Mark Foundation for Cancer ResearchMaine Technology InstituteNational Institutes of Health
2024-10-07Grant· $1.6M
2019-12-18Grant· $2.5M
2018-02-06Grant· $12.5M
Leadership Team
Lon Cardon
President and CEO
Mary Dickinson
Executive Vice President and Chief Scientific Officer
Recent News
2025-11-18
Company data provided by crunchbase