Olema Oncology · 2 months ago
Senior Medical Director, Clinical Development
Boston, Massachusetts
Full-time
Onsite
Senior Level
$315K/yr - $350K/yr
5+ years expOlema Oncology is dedicated to developing better medicines for breast cancer and beyond. As the Senior Medical Director, you will serve as the Oncology Physician Lead for palazestrant and play a pivotal role in advancing Olema’s late-stage clinical pipeline.
BiopharmaBiotechnologyHealth CareMedicalOncologyPharmaceutical
Responsibilities
Lead registration-enabling studies for palazestrant in combination with other therapies, including study design, regulatory engagement, and investigator collaboration
Partner across functions to define and implement clinical development strategies and plans for multiple programs
Serve as the primary medical expert and point of contact for clinical and scientific questions across internal and external stakeholders
Represent Olema in interactions with investigators, academic collaborators, thought leaders, and regulatory authorities
Maintain strong clinical and scientific acumen through ongoing engagement with the oncology community and key scientific meetings
Provide medical oversight and partner with CROs for Phase 3 programs and ensure alignment with Olema’s values, SOPs, and ethical standards
Lead the development and execution of clinical protocols, amendments, investigator brochures, study reports, abstracts, and manuscripts
Ensure scientific rigor and data integrity in partnership with cross-functional internal teams (i.e. Clinical Operations, Biostatistics, Safety) and CRO teams
Evaluate safety, pharmacology, and efficacy data from ongoing and completed studies to inform program strategy and decision-making
Contribute to regulatory submissions and communications
Collaborate with preclinical and translational scientists to develop and integrate biomarker strategies
Support data generation, publication planning, and external communication of study results
Qualification
Required
MD required
Board certification in Oncology, Hematology/Oncology, or related specialty; significant experience in breast cancer may substitute
5+ years of direct biotech or pharmaceutical experience in clinical development, with leadership in late-phase studies
Strong understanding of breast cancer treatment paradigms; experience with ER+/HER2- disease preferred
Proven success in designing, leading, and managing late-phase (registrational) studies in oncology; experience as a PI or academic breast cancer expert is also valued
Deep understanding of the drug development process and ability to translate strategy into action—meeting milestones, managing budgets, and adapting to change
Strong knowledge of GCP, FDA, and EMA/CHMP regulations; familiarity with other global regulatory standards is advantageous
Effective leadership in a matrixed environment, influencing without authority and driving cross-functional alignment
Exceptional communication skills—able to convey complex clinical data with clarity and purpose to both scientific and non-scientific audiences
Demonstrated problem-solving ability with urgency, focus, and creativity
Proven record of building collaborative, high-performing teams and partnerships
Highly organized, detail-oriented, and adaptable to fast-paced, evolving priorities
Strategic, decisive, and collaborative leader who inspires confidence and trust
Strong communicator with credibility among internal teams and external stakeholders
Relationship builder who thrives in a dynamic, mission-driven environment
Committed to lifelong learning and continuous professional growth
Preferred
Experience with ER+/HER2- disease preferred
Benefits
Equity
Bonus
Benefits
Competitive compensation and benefits package
Open, flexible, and friendly work environment
Company
Olema Oncology
Olema Oncology is a preclinical biotechnology company that develops new drugs for the treatment and prevention of breast cancer.
51-200 employees
H1B Sponsorship
Olema Oncology has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (4)
2024 (3)
2022 (2)
Funding
Current Stage
Public CompanyTotal Funding
$765.05MKey Investors
Paradigm BioCapital AdvisorsSilicon Valley BankVivo Capital
2025-11-20Post Ipo Equity· $190M
2024-12-02Post Ipo Equity· $250M
2023-09-05Post Ipo Equity· $130M
Leadership Team
Naseem Zojwalla
Chief Medical Officer
Shane Kovacs
Chief Operating and Financial Officer
Recent News
2025-12-25
thefly.com
2025-12-11
Company data provided by crunchbase