Bruker · 2 days ago
Scientist
Bruker Cellular Analysis (BCA) is focused on creating advanced optofluidic technology products that enhance cellular analysis. The NGS Scientist will develop and refine sequencing workflows to connect single-cell functional assays with genomic insights, collaborating with various teams to implement robust and scalable solutions.
ChemicalLife ScienceManufacturingMedical
Responsibilities
Develop and optimize Illumina NGS library preparation workflows (DNA and RNA) for single-cell and bulk assays
Integrate sequencing workflows into existing and emerging Beacon® applications for antibody discovery, functional genomics, and cell therapy research
Design, execute, and analyze sequencing experiments to evaluate workflow performance and enable new product capabilities
Establish and maintain QC metrics across the NGS pipeline, from input quality to sequencing readouts
Collaborate with automation and software engineering teams to implement scalable, reproducible sequencing workflows
Support root-cause investigations and troubleshooting of sequencing-related issues and contribute to continuous process improvement
Maintain accurate and complete documentation (SOPs, protocols, technical reports) in accordance with internal quality systems
Communicate experimental results, recommendations, and data insights to cross-functional project teams
Qualification
Required
M.S. or Ph.D. in Molecular Biology, Genomics, Bioengineering, or a related field (or equivalent industry experience)
2+ years of hands-on experience with Illumina sequencing workflows, including library prep, sequencing, and data QC
Strong understanding of nucleic acid biochemistry and standard molecular biology techniques (enzymatic reactions, purification, quantification)
Familiarity with single-cell sequencing, immune repertoire profiling, or multi-omic workflows
Experience with sequencing QC instrumentation (Bioanalyzer, TapeStation, qPCR, fluorometric assays)
Ability to interpret sequencing quality metrics and identify technical or process-related issues
Excellent communication skills and the ability to collaborate in a fast-paced, interdisciplinary environment
Preferred
Experience with automated NGS workflows (Agilent Bravo, Hamilton STAR, etc.) or high-throughput assay development
Exposure to basic bioinformatics tools (e.g., demultiplexing, alignment, QC review) or scripting in Python/R
Experience working within a QMS, ISO 13485, or regulated product development environment
Benefits
401(k) with company match
Employee stock purchase plan
Medical and dental plans
Life insurance
Short-term and long-term disability insurance
Employee assistance program
Paid time off including vacation, sick time and holidays
Company
Bruker
Bruker is a manufacturer of analytical and medical instruments covering NMR, ESR, FT-IR, X-RAY spectroscopy.
H1B Sponsorship
Bruker has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (1)
2022 (2)
Funding
Current Stage
Public CompanyTotal Funding
$1.01BKey Investors
Thomas Weisel Partners
2025-09-03Post Ipo Equity· $582M
2024-05-29Post Ipo Equity· $403.74M
2019-12-12Post Ipo Debt
Recent News
2026-01-13
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