Vor Bio · 2 months ago
Senior Data Manager
Boston
Full-time
Onsite
Senior Level
$175K/yr - $190K/yr
7+ years expVor BioPharma is focused on redefining the future of autoimmune care through innovative treatments. The Senior Data Manager will oversee data management activities for clinical trials, ensuring data quality and regulatory compliance while leading continuous improvement efforts within the department.
BiotechnologyHealth CareOncologyPharmaceutical
Responsibilities
Serves as data lead for one or more clinical trials, assuming responsibility for all data management activities, including access levels and permissions
Proactively drive quality and efficiency to meet timelines and milestones for data management in close collaboration with cross functional study team(s)
Conduct oversight of data management activities performed by the CROs and other 3rd party vendors (IRT, Safety, Lab, etc.) to meet Vor obligations and business objectives throughout study (ies) life cycle i.e. from protocol synopsis through database release and submission
Serve as a first point of contact for CRO DM partners to ensure established milestones and deliverables are met with the highest degree of quality
Ensure the CRO and other internal and external partners align and conform to data management expectations for the assigned compound and/or indication
Review and provide input for all DM documentation - CRF design and completion Guidelines, Data Management Plan, Data Transfer Specifications, etc
Oversee edit check specifications to support data collection and analysis required per protocol
Ensure the clinical database adheres to Clinical Data Acquisition Standards Harmonization guidelines allowing for optimal SDTM dataset programming. Suggest design for standard and non-standard data collection, identify any gaps in data collection, and challenge collection of unnecessary data
Participate in the creation of the clinical development plan, describing the clinical development strategy and possible innovative trial designs
Set quality expectations and timelines for data management deliverables and regularly follow up on data management milestones. Ensure inspection readiness at all times
Set expectations and communicate and a transparent, clear way and motive team members to work towards achieving the clinical goals
Follow department and company standard operating procedures (SOPs), forms, templates and policies. Provide feedback and update these guidelines as needed
Develop, review, and maintain all study Data Management documentation
Take responsibility for and guide effective quality control (QC) review and user acceptance testing (UAT) of the clinical database prior to its release into production, including oversight of staff performing these tasks
Ensure data are properly reviewed in accordance with the Data Management Plan (DMP) and guidelines and that cleaning is effective and timely
Provide input on study timelines, identify risks, and communicate mitigation strategies to the Project Manager
Provide input into improving the efficiency of data management tasks
Lead and participate in intradepartmental or interdepartmental process and quality improvement initiatives
Qualification
Required
Bachelor's Degree in programming, health-related sciences, or relevant field and 7+ years of Data Management experience
In depth knowledge of industry leading eCRF tools and well versed in industry trends and emerging technologies supporting data collection
Proficient experience using commercial clinical data management systems and/or EDC products e.g. Medidata Rave
Strong project management; exhibits expertise in metrics analysis and reporting methodologies
Extensive hands-on experience with clinical data management practices within industry sponsored clinical trials
Knowledge of clinical research, FDA & ICH, GCP, GCDMP, related regulatory requirements
Proven direct experience with data management tasks as well as DM vendor oversight to meet aggressive timelines of high-quality data deliverables
Contribute to the growth and development of the DM team
Excellent verbal and written communication skills
Professional attitude and strong interpersonal skills
Ability to work well with a multi-disciplinary team of professionals
Flexible attitude with respect to work assignments and new learning
Ability to prioritize workload
Superior attention to detail
Understanding of clinical research and the relationship of Data Management in the clinical study process
Strong technical aptitude and ability to adapt to multiple data management platforms
Strong knowledge of electronic data capture (EDC) clinical data management systems
Strong computer skills (Microsoft Office Suite, Medidata Rave) and ability to understand and adapt to various information technology (IT) systems
Benefits
Comprehensive health coverage
Flexible paid time off
Generous parental leave
Competitive 401(k)
Education assistance
Wellness resources
Financial security
Company
Vor Bio
Vor Bio is a clinical-stage biotechnology company transforming the treatment of autoimmune diseases.
2-10 employees
H1B Sponsorship
Vor Bio has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (6)
2024 (5)
2023 (6)
2022 (10)
2021 (1)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$748.4MKey Investors
RA Capital Management
2025-12-15Post Ipo Equity· $150M
2025-11-10Post Ipo Equity· $100M
2025-06-24Post Ipo Equity· $175M
Leadership Team
Jean-Paul Kress
Chairman and CEO
Dallan Murray
EVP, Chief Commercial Officer
Recent News
GlobeNewswire
2025-12-15
2025-12-15
Company data provided by crunchbase