Treeline · 9 hours ago
Senior Clinical Trial Manager
Watertown, Massachusetts, United States
Full-time
Onsite
Senior Level
$153K/yr - $198K/yr
5+ years expTreeline Biosciences is a growing company in the clinical development sector, seeking a Senior Clinical Trial Manager to provide trial management support for their oncology programs. The role involves managing clinical studies in compliance with regulations, overseeing CROs and study vendors, and identifying project risks while ensuring timely and coordinated activities.
BiotechnologyHealth CareLife ScienceMedicalPrecision Medicine
Responsibilities
Clinical Operations point of contact for execution of clinical studies in compliance with ICH/GCP, Regulatory Authorities' regulations/guidelines, and applicable SOPs/Work Instructions
Manage clinical CRO(s) and other study vendors from initial contact through to final study deliverables
Lead external (CRO) trial management team, to ensure conduct in accordance with State and Federal regulations, GCP regulations, ICH guidelines, and internal SOPs
Ensure coordination of the CRO activities are timely, coordinated and complete, including but not limited to clinical monitoring, data management, medical monitoring, medical writing, statistics and safety/pharmacovigilance
Provide operational input into study documents including clinical protocol, informed consent, CRFs, any and all CRO study documents/study plans
Develop, manage, and maintain study deliverables [i.e. timelines, study plans, etc.] through collaboration with internal and external stakeholders
Proactively identify potential study risks and develop/implement actions to avoid or mitigate potential risks
Develop/coordinate study training and associated materials for study team, investigational sites, and vendors in collaboration with medical and scientific colleagues both internally and externally
Attend (in person and virtual) study site visits, such as pre-study selection visits, site initiation visits, and PI engagement meetings
Responsible for supporting the management, oversight and maintenance of the Trial Master File (TMF) held by the CRO
Qualification
Required
Bachelor's degree, or equivalent, in a biomedical, life science or related field of study
5-8+ years of trial management experience as primary Clinical Trial Manager (or equivalent) within Pharma, Biotech or CRO; Oncology experience required
Strong understanding of global regulatory and compliance requirements for clinical research
Strategic understanding of how outcomes, budgets, and timelines are impacted by decisions
Outstanding teamwork, organizational, interpersonal, and problem-solving skills
Effective communicator both verbally and in written form
Ability to influence and collaborate well with colleagues and partners in a fast-paced growing development company
Company
Treeline
Treeline (or Treeline Biosciences) is a privately held, clinical-stage biopharma company that aspires to make medicines at the highest level.
51-200 employees
H1B Sponsorship
Treeline has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (4)
2023 (3)
2021 (1)
Funding
Current Stage
Growth StageTotal Funding
$1.09BKey Investors
AI Life Sciences Investments LLCKohlberg Kravis Roberts
2025-09-03Series A· $200M
2024-10-17Undisclosed· $421M
2022-10-11Series A· $261.27M
Leadership Team
Spencer Smith
Chief Financial Officer
Recent News
2025-10-04
2025-10-01
Genetic Engineering News
2025-09-30
Company data provided by crunchbase