Exelixis · 10 hours ago
Sr Scientist I (Formulations)
Alameda, CA
Full-time
Onsite
Mid, Senior Level
$116K/yr - $166K/yr
5+ years expExelixis is a company focused on drug product development for oncology products. The Senior Scientist I will oversee formulation, process development, and optimization of small molecule oral dosage forms, while also coordinating lab activities and supporting technology transfer and commercialization efforts.
BiotechnologyHealth CarePharmaceutical
Responsibilities
Develop oral solid dosage form for oncology products using various formulation technologies
Design formulation development studies including lab scale and scale-up manufacturing processes for oral solid dosage form
Identify, critical quality attributes and process parameters and implement appropriate process controls for the manufacturing process
Work in high potency lab using PAPR and appropriate lab safety procedures
Troubleshooting skills in formulation/process issues for oral solid dosage forms
Apply methodical approach in selection of vehicles, excipients and/or new technologies appropriate to prepare formulations of novel investigational small molecules to support non-clinical studies
Apply statistical design of experiments to optimize and scale-up formulations and manufacturing process
Knowledge of enabling technologies such as solid dispersion, lipid or microemulsion, oral liquid formulation is a plus
Participation in project teams and internal/external collaborations, and preparation and review of regulatory/CMC documents
Possess excellent writing and verbal communication skills and strong interpersonal skills
Qualification
Required
BS/BA degree in pharmaceutics, or pharmaceutical sciences, bioengineering, biophysics, chemical engineering and seven years of related experience; or
MS/MA degree in pharmaceutics, or pharmaceutical sciences, bioengineering, biophysics, chemical engineering and five years of related experience; or
PhD in pharmaceutics, or pharmaceutical sciences, bioengineering, biophysics, chemical engineering, and zero or more years of related experience, or
Equivalent combination of education and experience
Experience in Pharmaceutical/Biotech industry preferred
Must have proven skills in the areas of solid oral drug product formulation development
Hands on experience in high shear granulation, roller compaction, direct compression, aqueous and solvent-based coating is required
Knowledge of formulation development and process optimization/scale up of solid oral dosage forms
Strong knowledge and experience of the various phases of drug development for oral dosage forms is required
Familiarity and working knowledge of current Good Manufacturing Practices (cGMP)/International Conference on Harmonization (ICH) regulations, with experience working in a GMP facility is required
Proficient with broad use of computer applications such as MS Office
Applies strong analytical and excellent verbal and written communication skills
Identifies and implements methods and procedures to achieve results
Performs a variety of complicated tasks with a wide degree of creativity and latitude
Has complete understanding and wide application of technical principles, theories, concepts and techniques
Has good general knowledge of other related disciplines
Applies strong analytical and business communication skills
Preferred
Experience with statistical tools to design and evaluate experiments for formulation and process development preferred
Experience with other dosage forms or advanced formulations (e.g. controlled release) is a plus
Knowledge of enabling technologies such as solid dispersion, lipid or microemulsion, oral liquid formulation is a plus
Operation of various scientific instrumentation such as, High Performance Liquid Chromatography (HPLC), Fourier Transfer Infrared Spectroscopy (FTIR), Thermogravimetric Analysis (TGA), and Differential Scanning Calorimeter (DSC), etc. is a plus
Benefits
401k plan with generous company contributions
Group medical, dental and vision coverage
Life and disability insurance
Flexible spending accounts
Discretionary annual bonus program
Sales-based incentive plan
Opportunity to purchase company stock
Receive long-term incentives
15 accrued vacation days in their first year
17 paid holidays including a company-wide winter shutdown in December
Up to 10 sick days throughout the calendar year
Company
Exelixis
Exelixis works is focused on discovering, developing and commercializing therapies for the treatment of cancer and other serious diseases.
1001-5000 employees
H1B Sponsorship
Exelixis has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (39)
2024 (25)
2023 (25)
2022 (28)
2021 (29)
2020 (15)
Funding
Current Stage
Public CompanyTotal Funding
$514MKey Investors
Deerfield
2015-07-23Post Ipo Equity· $135M
2012-02-16Post Ipo Equity· $65M
2010-06-03Post Ipo Debt· $160M
Leadership Team
Michael Morrissey
President and CEO
Christopher Senner
Executive Vice President and CFO
Recent News
2026-01-12
The Motley Fool
2026-01-09
Company data provided by crunchbase