Allen Institute · 6 hours ago
Scientist I - Integrative Analysis of SEA-AD and Community Multiomics Datasets
Allen Institute is dedicated to advancing health through understanding the principles that govern life. The Scientist I role focuses on integrating, analyzing, and interpreting multiomics datasets related to Alzheimer's disease, collaborating with a team to develop computational tools and methodologies.
Neuroscience
Responsibilities
Collaborate with SEA-AD and SEA-AD IAC members and outside investigators to ensure community multiomic datasets are re-processed, their metadata is harmonized, and relevant secondary data types are obtained (e.g. whole genome sequencing, nuclear imaging, or blood based biomarkers)
Adapt existing or develop novel computational tools to rigorously quantify changes in cell types in Alzheimer’s disease across community datasets
Associate gene expression and chromatin accessibility changes with relevant and available donor metadata or secondary data types
Compare cell type changes across disease progression between studies regions to identify common early changes that may inform biomarkers
Interact with scientists from diverse backgrounds and perspectives to design analytical approaches and refine computational strategies
Work with experimental scientists to design experiments to validate predictions of disease function
Participate in a highly interactive and multidisciplinary environment
Publish and present findings in peer-reviewed journals and scientific conferences
Qualification
Required
Ph.D. in Neuroscience, Computational Neuroscience, Computer Science, Applied Math, or related field; or equivalent combination of degree and experience
Fluency programming in Python in high performance computing
Fluency with version control systems (e.g. Git/Github)
Familiarity with analysis of RNA-sequencing or related data types
Preferred
Experience with modeling disease or developmental trajectories, or related computational studies
Additional experience in computational analysis and statistical assessment of biological datasets in other modalities such as spatial statistics, ATAC-seq analysis, computational anatomy, or related fields
Previous work on studying Alzheimer's disease or other neurodegenerative diseases
Familiarity with additional programming languages (e.g., R)
Experience with GPU-based deep learning
Ability to work effectively in a highly collaborative environment
Strong written and verbal communication skills
Ability to work independently and collaboratively
Strong publication track record
Benefits
Medical
Dental
Vision
Basic life insurance
401k plan
Paid time off
Company
Allen Institute
The Allen Institute is dedicated to answering some of the biggest questions in bioscience and accelerating research worldwide.
H1B Sponsorship
Allen Institute has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (41)
2024 (33)
2023 (25)
2022 (26)
2021 (17)
2020 (7)
Funding
Current Stage
Late StageRecent News
2025-12-25
2025-12-24
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