Alumis · 2 months ago
Senior Medical Director, Rheumatology
South San Francisco
Full-time
Onsite
Senior Level, Lead/Staff
$300K/yr - $358K/yr
5+ years expAlumis Inc. is a precision medicines company focused on transforming the lives of patients with autoimmune diseases. They are seeking an experienced Senior Medical Director in Clinical Development to lead clinical drug development activities in rheumatology, overseeing studies and collaborating with cross-functional teams to advance clinical programs.
BiotechnologyHealth CareLife ScienceMedicalPrecision Medicine
Responsibilities
Serve as the physician lead for LUMUS, a 388-patient Phase 2b clinical trial designed to evaluate the efficacy, safety, and pharmacokinetics of multiple doses of ESK-001 in adult patients with moderately to severely active, autoantibody-positive SLE
Provide leadership of in-stream data reviews and reconciliation efforts
Hold authorship of clinical portions of key study documents, such as Protocol Amendments and Regulatory Submissions
Provide oversight of the LUMUS medical monitor
Participates in external scientific engagement, including peer-to-peer interactions with MDs
Broadly represent the interests of Alumis as a leader, supporting corporate initiatives across rheumatology
Coach, manage, inspire, and support team members to achieve goals by leveraging a focused and collaborative mindset
Maintain the highest levels of integrity and standards for scientific inquiry in drug development
Earn the full trust and respect of key internal and external stakeholders by establishing a reputation as a strategic and highly productive partner
Provide hands-on leadership, apply knowledge and expertise, and partner seamlessly with the operations team to help make LUMUS thrive
Focus on improving and maintaining study data quality, including cross-referencing of the main efficacy endpoints
Qualification
Required
MD (or ex-US equivalent) with board certification in Rheumatology
5+ years of clinical development experience; having a background in lupus clinical trials is desired
Proven leadership skills, as evidenced by having managed people within a pharmaceutical company or in a clinical/academic environment
Ability to assess, understand, and communicate continuously expanding medical and scientific information
Proven professional track record of strategic, organizational, and executional skills to support project planning across multiple activities, with the ability to anticipate and prioritize one's workload across multiple projects of equal importance
Proven ability to approach deliverables in an organized manner with attention to detail and to meet timelines in a fast-paced environment
Established ability to work across diverse teams in a matrixed organizational structure, both as a leader and as part of a cross-functional team
Strong interpersonal, influencing, presentation, and communications skills (both written and verbal) to effectively address all levels within an organization
Ability to work autonomously and with a high level of independence
Willingness to travel to Alumis' HQ in South San Francisco for one week out of every month
Benefits
Health insurance premiums paid at 90% for employee, 80% for dependents
Free access to Genentech Bus & Ferry Share program
$100 monthly cell phone stipend
Unlimited PTO for Exempt employees
Free onsite gym and a kitchen stocked with yummy snacks and drinks!
Company
Alumis
Alumis is a precision medicine company focused on the discovery, development and treatment of autoimmune disorders.
51-200 employees
Funding
Current Stage
Public CompanyTotal Funding
$917.19MKey Investors
Foresite CapitalMatrix Capital Management
2026-01-07Post Ipo Equity· $345.1M
2025-11-19Post Ipo Secondary· $3.09M
2024-07-23Post Ipo Equity· $40M
Leadership Team
Martin Babler
Chairman, President and CEO
K
Ken A Brameld
Fellow, Head of Discovery
Recent News
thefly.com
2026-01-16
Company data provided by crunchbase