Associate Scientist II, Neuroscience jobs in United States
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PTC Therapeutics, Inc. · 1 month ago

Associate Scientist II, Neuroscience

PTC Therapeutics is a global commercial biopharmaceutical company committed to improving the lives of those with rare diseases. The Associate Scientist II, Neuroscience will conduct scientific experiments to support research and drug discovery, focusing on the identification of New Chemical Entities and the advancement of research programs.

BiotechnologyHealth CareTherapeutics
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Under general guidance, executes experiments, interprets, and communicates results as part of multi-disciplinary team(s)
Applies relevant scientific principles and techniques to research problems
Maintains detailed laboratory notebooks
Maintains knowledge of state-of-the-art principles and techniques
Ability to independently troubleshoot experiments - designing controls, generating interpretable data
Presents findings internally and contributes to the publication of the work of the project team
Contributes to the development of patent applications as appropriate
Complies with all safety requirements
Contributes to laboratory needs, such as stockroom maintenance and ordering supplies
Involved in general lab duties as assigned
Assist in target deconvolution studies using a wide array of methodologies (including flow cytometry, ELISA, Western blot, RT-qPCR)
Executes weekly cell-based screening assays to support hit to lead optimization efforts for early-stage discovery programs
Maintains multiple cell lines (thawing, passaging, seating) to support in vitro screening assays
Routinely uploads and reports data in a timely fashion which may also include communicating any delays or changes in workflow to a cross-disciplinary team
Provides support for the design and optimization of new assays, the goal of which is the identification of additional hits
Profiles selected compounds to better understand compound mechanism of action in additional cells and tissues

Qualification

Flow cytometryMammalian tissue cultureCell biologyMolecular biologyData analysisAssay optimizationScientific communicationMicrosoft OfficeAttention to detailProblem-solvingTime managementTeam collaboration

Required

Bachelor's degree in a Biology scientific discipline, preferably Biology or Neuroscience or Immunology with a minimum of 6 years' experience, OR, Master's degree in a scientific discipline with a minimum of 2 years of relevant experience
Experience with multi-color flow cytometry and immunophenotyping primary human cells
Mammalian tissue culture experience with excellent sterile technique required
Knowledge of basic Cell biology and Molecular biology
Exceptional attention to detail and time management skills
Strong analytical and problem-solving skills
Demonstrates technical proficiency, and the ability to collaborate with others on cross functional teams in a fast-paced, matrixed, environment consisting of internal and external team members
Possesses knowledge of scientific principles and concepts and keeps current with relevant scientific literature
Proficiency with Microsoft Office- preferably MS Excel and MS PowerPoint
Effective verbal and written communication and skills
Analytical thinker with problem-solving skills and the ability to adapt to changing priorities and deadlines
Effective planning, organization and time management skills including the ability to support and prioritize multiple projects

Preferred

Basic understanding of adaptive and innate immune system, especially as they relate to peripheral and nervous system inflammatory diseases
Familiarity with establishing and routinely executing reproducible high-throughput assays
Proficiency with standard data analysis workflows, data visualization tools, and basic statistical analysis highly valued
Knowledge of and ability to use standard molecular, cell biology, and immunology techniques
Deep understanding in assay optimization and troubleshooting required

Benefits

Short- and long-term incentives
Medical, dental, vision, and retirement savings plans

Company

PTC Therapeutics, Inc.

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PTC is a patient-centered biopharmaceutical company focused on discovering, developing & commercializing medicine for children and adults living with rare and serious disease.

H1B Sponsorship

PTC Therapeutics, Inc. has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (7)
2024 (9)
2023 (14)
2022 (31)
2021 (13)
2020 (6)

Funding

Current Stage
Public Company
Total Funding
$1.57B
Key Investors
Brookside CapitalCredit Suisse First Boston
2022-10-27Post Ipo Equity· $1B
2020-05-14Post Ipo Equity· $140.95M
2015-08-14Post Ipo Debt· $150M

Leadership Team

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Matthew B. Klein
Chief Executive Officer and President
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Stuart Peltz
CEO
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Company data provided by crunchbase