Regeneron · 1 day ago
Principal Engineer
Sleepy Hollow, NY
Full-time
Onsite
Senior Level, Lead/Staff
$127K/yr - $207K/yr
5+ years expRegeneron is a biotechnology company that is seeking a Principal Engineer for their IT Enterprise Services department. The role involves overseeing the delivery of high-quality M365 services, ensuring compliance and security, and providing engineering support for operational projects.
BiopharmaBiotechnologyPharmaceutical
Responsibilities
Responsible for engineering compliance, security, and effective delivery of the O365 Services throughout Regeneron
Develop and document the build/operations specifications for any new or existing M365 services and related core components
Engineer monitoring, control, and support of the service; ensuring systems, methodologies and procedures are in place and followed
Assist the Service Delivery Team in providing engineering services and support in operational projects and develop a strong understanding of projects impacting the M365 environment and ensuring service impact is minimized and agreed
Be accountable for the quality of the M365 engineering service and performance; ensuring future demand from growth and projects is understood and factored into capacity plans for all associated systems
Participate and lead architectural discussions, make recommendations for Service improvements, and ensure actions are followed through to completion in a timely manner
Provide engineering direction for Microsoft O365 products with specialized skills in Exchange, Azure, OneDrive, OneNote, SharePoint, Teams, and Skype
Experience with Microsoft Cloud Solutions design, and operations is a must
Strong knowledge of at least one programming or scripting language (like PowerShell, Python, etc.)
Hands-on experience with the implementation of Azure Information Protection is expected
In-depth knowledge and experience in configuring M365 security features including AIP, DLP, ATP, IAM/RBAC, and SIEM is a must
Responsible for the Level 3 day-to-day delivery of the service to the business as expressed in the Statement of Work
Qualification
Required
Bachelor's degree in the field of computer science, information systems, computer engineering or 5+ years of relevant work experience
Responsible for engineering compliance, security, and effective delivery of the O365 Services throughout Regeneron
Develop and document the build/operations specifications for any new or existing M365 services and related core components
Engineer monitoring, control, and support of the service; ensuring systems, methodologies and procedures are in place and followed
Assist the Service Delivery Team in providing engineering services and support in operational projects and develop a strong understanding of projects impacting the M365 environment and ensuring service impact is minimized and agreed
Be accountable for the quality of the M365 engineering service and performance; ensuring future demand from growth and projects is understood and factored into capacity plans for all associated systems
Participate and lead architectural discussions, make recommendations for Service improvements, and ensure actions are followed through to completion in a timely manner
Provide engineering direction for Microsoft O365 products with specialized skills in Exchange, Azure, OneDrive, OneNote, SharePoint, Teams, and Skype
Experience with Microsoft Cloud Solutions design, and operations is a must
Strong knowledge of at least one programming or scripting language (like PowerShell, Python, etc.)
Hands-on experience with the implementation of Azure Information Protection is expected
In-depth knowledge and experience in configuring M365 security features including AIP, DLP, ATP, IAM/RBAC, and SIEM is a must
Responsible for the Level 3 day-to-day delivery of the service to the business as expressed in the Statement of Work
Preferred
Deep knowledge of Microsoft 365 Infrastructure technologies, data center, server, virtualization, storage, and disaster recovery/business continuity
Demonstrated skills in Microsoft O365 products with specialized skills in Exchange, Azure, OneDrive, Teams, OneNote, SharePoint, and Skype
Demonstrated skills in SMTP email relay, AntiSpam, AntiMalware, AntiPhishing, and Data Leak Prevention filtering services
Service Management or Engineering Support in a large-scale and diverse environment of incident management, escalation procedures and related disciplines
Experience designing and developing highly available infrastructure capable of 24x7x365 business operations with a track record of managing teams that supported engineering highly available services
Benefits
Health and wellness programs (including medical, dental, vision, life, and disability insurance)
Fitness centers
401(k) company match
Family support benefits
Equity awards
Annual bonuses
Paid time off
Paid leaves (e.g., military and parental leave)
Company
Regeneron
Regeneron Pharmaceuticals specializes in the discovery, development, and commercialization of innovative medicines.
10001+ employees
H1B Sponsorship
Regeneron has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (157)
2024 (128)
2023 (128)
2022 (137)
2021 (104)
2020 (122)
Funding
Current Stage
Public CompanyTotal Funding
$15.93MKey Investors
U.S. Department of Health & Human Services
2024-07-11Post Ipo Equity· $2.03M
2023-10-18Post Ipo Equity· $5M
2016-08-22Post Ipo Equity· $8.9M
Leadership Team
Aris Baras
Senior Vice President, Regeneron Pharmaceuticals, General Manager, Regeneron Genetics Center
Bari Kowal
Senior Vice President, Head Development Operations & Portfolio Management
Recent News
Pharmaceutical Technology
2026-01-16
2026-01-16
Company data provided by crunchbase