Howard Hughes Medical Institute (HHMI) · 5 hours ago
Postdoctoral Scientist- Kim and Abdus-Saboor Lab
Princeton, NJ
Full-time
Hybrid
Senior Level
$70K/yr - $91K/yrHoward Hughes Medical Institute (HHMI) is seeking an energetic, curious, and driven Postdoctoral Scientist with expertise in protein engineering to join their research teams. The role involves employing high-throughput screening assays and protein large language models to design new activity-dependent labeling enzymes and transcriptional reporters, with opportunities for validation and application in mice through collaborations between the Kim Lab and Abdus-Saboor Lab.
BiotechnologyClinical TrialsHealth CareMedicalMedical Device
Responsibilities
Employ high-throughput screening assays and protein large language models to design new activity-dependent labeling enzymes and transcriptional reporters optimized for application in the peripheral nervous system
Validate and apply these tools in mice through collaborations/cross-training between the two labs
Work closely with members of the Kim lab for tool engineering and initial validation
Work closely with members of the Abdus-Saboor lab for tool testing and application in the peripheral nervous system
Attend group meetings of both the Kim Lab and the Abdus-Saboor Lab with some combination of in-person and hybrid attendance
Qualification
Required
A Ph.D. in bioengineering, chemical biology, neuroscience, or related field of science
Advanced experience in creative design for molecular tool engineering
Ability to learn quickly and to work both independently and as part of a team
High level of research integrity and motivation
Positive attitude with a problem-solving, resilient approach
Resourcefulness in overcoming challenges, and the ability to adapt and thrive in a fast-paced environment
Willingness to fully participate in lab and departmental activities, to positively engage with other team members and promote their success (e.g., by reviewing manuscripts, participating in practice talks), mentor junior colleagues, and contribute to an inclusive and productive research climate
Experience and prior training in some of the following areas: Protein engineering (rational design, directed evolution, computational design, etc.), Molecular biology (cloning, AAV handling), Cell culture testing (HEK cells, primary neuron culture), Biochemical assays and screening (antibody staining, fluorescence-based imaging assays, FACS, cell stimulation read-outs), Animal testing in the brain, spinal cord, and/or peripheral nervous system (AAV injection, perfusions, slicing), Imaging (epifluorescence and confocal), Data analysis (quantification of fluorescence labeling)
Benefits
Comprehensive health and welfare benefits
One on one mentorship with PIs of both labs
Opportunity to work across multiple disciplines, including cellular to animal work
Exposure to cutting-edge scientific research and opportunities for professional development
Authorship on independent and collaborative scientific publications
Opportunities to attend domestic conferences in addition to departmental and HHMI retreats to present scientific findings
Being part of the larger scientific communities at both Princeton University and Columbia University
Competitive pay
Exceptional health benefits
Retirement plans
Time off
A range of recognition and wellness programs
Company
Howard Hughes Medical Institute (HHMI)
Founded in 1953, HHMI invests in scientists at all career stages who make discoveries that advance human health and our fundamental understanding of biology.
Founded in 1953
1001-5000 employees
H1B Sponsorship
Howard Hughes Medical Institute (HHMI) has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (93)
2024 (137)
2023 (135)
2022 (162)
2021 (133)
2020 (127)
Funding
Current Stage
Late StageTotal Funding
$1MKey Investors
Salt Lake Community College
2017-08-31Grant· $1M
Leadership Team
Boyana Konforti
Director of Scientific Strategy & Development
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