Bruker · 5 hours ago
Staff Scientist, Assay Development and Data Analytics
San Jose, CA
Full-time
Onsite
Lead/Staff
$115K/yr - $204K/yr
8+ years expBruker is one of the world’s leading analytical instrumentation companies enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. They are looking for a Staff Scientist to contribute to the optimization and development of advanced bioassays for spatial omics applications, working closely with a multidisciplinary team to conduct experiments and analyze large data sets.
ChemicalLife ScienceManufacturingMedical
Responsibilities
Support and spearhead the method development and optimization of novel molecular biology assay schemes for spatial omic applications including molecular barcoding, fluorophore marking, nucleic acid hybridization, amplification and sequencing techniques, and probe library preparation
Support the optimization of probe chemistry and probe-based sequencing with spatial multi-omic profiling applications
Help develop the optimization of sample preparation methods such as tissue/cell fixation and permeabilization
Independently plan and execute experiments, accurately record details, provide in-depth analysis, and report results through documentation and presentations
Support the generation of test samples through cell culture and/or tissue preparation
Assist/lead in the analysis of large and complex data sets, including developing routines for streamlined and automated data pipelines
Prepare assay reagents and other components
Work within multidisciplinary teams at all stages of product development
Assist with research projects to profile spatial genomics. Collaborate with other team members on research studies
Support and lead elements of the development, verification and validation of product related kits and reagents
Analyze specimens on imaging instrumentation. Analyze research data and assist with data interpretation
Prepare research reports and share findings with the team. Write protocols, develop procedures, and maintain accurate records
Clearly communicate and present results; contribute data for making critical design decisions
Qualification
Required
BS/MS/PhD in biophysics, chemical/biomolecular engineering, molecular biology, biochemistry, cell biology, or a related field and 8-12+ (BS/MS) and 3-5+ (PhD) years of hands-on molecular biology experience in an academic or industrial setting
Strong background in programming for analysis of complex and large data sets, preferably in python
Proficient in standard molecular biology techniques such as sample preparation, nucleic acid amplification and purification (RNA/DNA), qPCR, and DNA sequencing or similar molecular biology techniques
Experience with microscopy
Knowledge of advanced fluorescence in situ hybridization (FISH) or other in situ fluorescence probed-based techniques
Understanding of basic absorption and emission spectroscopy
Highly motivated with excellent attention to detail
Good communication (oral and written) and collaboration skills
Experience in cell culture and tissue preparation techniques
Experience in troubleshooting and optimization of molecular biology assays including reagent formulation and workflow optimization
Experience with experimental design and data analysis
Must be capable of performing complex multi-step experiments with detailed and diligent attention to technique and protocols with accurate record keeping
Desire to be part of a rapidly evolving organization, which requires real-time communication, flexibility, working well with others, and a willingness to learn new techniques and methods
Preferred
Experience in product development including product release
Familiarity with basic statistical data and error analysis
Familiarity with single cell and/or spatial transcriptomics, fixation chemistry, Design of Experiments (DOE)
Experience in developing novel computational tools to analyze Hi-C or epigenomic datasets, and deriving biologically meaningful insights from the observed structural and regulatory patterns
Advanced fluorescence imaging techniques
Experience in microscopy image analysis
Experience with use and troubleshooting of automated equipment, preferably for imaging applications
Benefits
401(k) with company match
Employee stock purchase plan
Medical and dental plans
Life insurance
Short-term and long-term disability insurance
Employee assistance program
Paid time off including vacation, sick time and holidays
Company
Bruker
Bruker is a manufacturer of analytical and medical instruments covering NMR, ESR, FT-IR, X-RAY spectroscopy.
5001-10000 employees
H1B Sponsorship
Bruker has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2023 (1)
2022 (2)
Funding
Current Stage
Public CompanyTotal Funding
$1.01BKey Investors
Thomas Weisel Partners
2025-09-03Post Ipo Equity· $582M
2024-05-29Post Ipo Equity· $403.74M
2019-12-12Post Ipo Debt
Leadership Team
Frank Laukien
Chief Executive Officer
Jason Faessler
Senior Vice President Finance
Recent News
2025-12-20
Investor's Business Daily
2025-11-20
Research & Development World
2025-11-19
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