Mount Sinai Health System · 1 month ago
Postdoctoral Fellow-MSH-30025-245
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, and they are seeking a Postdoctoral Fellow to investigate the role of TET2-mutant clonal hematopoiesis in cancer progression. The fellow will utilize advanced techniques to explore the interactions between mutant immune cells and the metastatic environment, contributing to impactful research in cancer biology.
Health CareHospitalMedical
Responsibilities
Generate genome-edited hematopoietic stem/progenitor cells (HSPCs) using CRISPR/Cas9
Perform xenotransplantation of human HSPCs into immunodeficient mice
Analyze bone marrow and tumor samples via flow cytometry, immunohistochemistry, and histology
Conduct bioluminescence imaging to monitor metastasis progression
Assist in spatial transcriptomics using 10x Visium HD and single-cell RNA sequencing workflows
Maintain primary cell cultures, perform viral transduction, and cytokine assays
Participate in manuscript preparation and presentation of findings
Qualification
Required
PhD in cancer biology, hematology, immunology, or a related biomedical discipline
Demonstrated experience in molecular biology and murine models
Strong communication skills and ability to work independently and collaboratively in a team
Prior experience with CRISPR-based genome editing and/or xenograft models
Preferred
Familiarity with hematopoietic stem cell biology and immune phenotyping
Experience analyzing high-dimensional datasets (e.g., scRNA-seq)
Company
Mount Sinai Health System
Mount Sinai Health System delivers integrated medical care, research, and medical education through its network.
H1B Sponsorship
Mount Sinai Health System has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)
Funding
Current Stage
Late StageTotal Funding
$41.9MKey Investors
National Institutes of HealthHearst Health Prize.Multiple Myeloma Research Foundation
2024-11-11Grant· $7M
2024-06-06Grant· $0.1M
2023-11-02Grant· $7M
Leadership Team
Recent News
Digital Journal
2026-01-08
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