St. Jude Children's Research Hospital · 9 hours ago
Lead Researcher Antibody Discovery
Memphis, TN
Full-time
Onsite
Mid, Senior Level
$60K/yr - $105K/yr
5+ years expSt. Jude Children's Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The Lead Researcher for Antibody Discovery will develop and implement strategies to improve molecular biology processes and support antibody discovery efforts.
BiotechnologyCharityHealth CareHealth DiagnosticsHospitalMedicalNon Profit
Responsibilities
Work closely with mAb discovery platforms to support molecular biology workflows; design and execute construct generation for antibody expression
Perform DNA preparations to generate high-quality plasmid material for mammalian cell transfection
Develop and optimize high-throughput mammalian cell-based production platforms for recombinant antibodies, antigens, and other biologics
Establish scalable transient and stable expression workflows in CHO, HEK293, and other mammalian expression systems
Purification using AKTA chromatography systems
High-Performance Liquid Chromatography Size Exclusion Chromatography (HPLC-SEC) analysis of purified proteins
Molecular assessment of early-stage development candidates (polyreactivity ELISA, CE-SDS, SEC-MALS, DSF)
Maintain accurate and timely ELN data
Qualification
Required
Bachelor's degree in a relevant scientific area is required
5+ years of research experience is required
3+ years of experience is required with a Master's degree
No prior experience required with a PHD
Strong knowledge and experience in understanding and application of underlying principles related to techniques being performed
Experience in R&D methods and processes in lab setting, and execution of research projects for the laboratory preferred
Proven performance in earlier role/comparable role
Preferred
Experience with modern AKTA chromatography systems (FPLC) for affinity capture and SEC chromatography
Experience with high-throughput automated protein purification systems (e.g. Kingfisher)
Experience with antibody-related bioinformatic/software packages
Expertise in high-throughput molecular biology approaches for construct generation
Experience with mAb characterization techniques (FACS, BLI, epitope binning)
Benefits
Comprehensive healthcare
Tuition assistance for continued education
Exceptional work-life balance with ample paid time off
Professional growth opportunities
An on-site gym
An employee pharmacy
Company
St. Jude Children's Research Hospital
St.
5001-10000 employees
H1B Sponsorship
St. Jude Children's Research Hospital has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (370)
2024 (316)
2023 (309)
2022 (255)
2021 (251)
2020 (201)
Funding
Current Stage
Late StageTotal Funding
$62.4MKey Investors
Kia MotorsKBR Charity Golf TournamentHyundai Hope On Wheels
2025-05-12Grant· $1.5M
2024-10-28Grant
2024-08-28Grant· $0.4M
Leadership Team
Judy A. Habib
Chair, Board of Directors
Recent News
24-7 Press Release Newswire
2025-12-25
2025-12-22
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