Legend Biotech · 11 hours ago
Promoter Engineering Co-Op
Philadelphia, PA
Full-time
Onsite
New GradLegend Biotech is a global biotechnology company dedicated to treating life-threatening diseases. They are seeking a Promoter Engineering Co-Op to contribute to the design and functional validation of synthetic and natural promoters for T-cell gene expression, combining computational analysis with hands-on lab work to advance gene regulation strategies in gene therapy research.
BiotechnologyHealth CareLife ScienceOncologyTherapeutics
Responsibilities
Assist in designing synthetic and natural promoters for T-cell specific gene expression using bioinformatics tools and literature mining
Perform cloning of promoter sequences into lentiviral vectors using standard molecular biology techniques (PCR, restriction digestion, ligation, Gibson assembly)
Maintain mammalian cell lines and primary T cells; support transfection and transduction experiments
Conduct reporter assays (e.g. luciferase, GFP) to evaluate promoter strength and specificity in T cells or cell lines
Analyze experimental data using software such as GraphPad Prism, Excel, and basic statistical methods
Maintain accurate lab notebooks and present findings in team meetings
Qualification
Required
Currently enrolled in Graduate programs (Master's) in bioinformatics, data science, computer science, computational biology, or related field
Basic understanding of molecular biology and cell culture principles
Strong interest in promoter engineering and gene regulation with an understanding of transcriptional control mechanisms
Experience with bioinformatics tools or programming languages (Python, R) is a plus
Familiarity with laboratory techniques such as pipetting, buffer preparation, and aseptic handling
Strong attention to detail, organizational skills, and ability to work independently and in a team environment
Excellent communication and documentation skills
Benefits
Medical, dental, and vision insurance
401(k)-retirement plan with company match that vest fully on day one
Equity and stock options
Eight weeks of paid parental leave after just three months of employment
Paid time off policy that includes 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays
Flexible spending and health savings accounts
Life and AD&D insurance
Short- and long-term disability coverage
Legal assistance
Supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance
Commuter benefits
Family planning and care resources
Well-being initiatives
Peer-to-peer recognition programs
Company
Legend Biotech
Legend Biotech is a biopharmaceutical company that develops and commercializes novel cell therapies for oncology.
Founded in 2014
1001-5000 employees
H1B Sponsorship
Legend Biotech has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (30)
2024 (11)
2023 (14)
2022 (7)
2021 (6)
2020 (13)
Funding
Current Stage
Public CompanyTotal Funding
$750.45M2023-05-05Post Ipo Equity· $350M
2022-07-25Post Ipo Equity· $250M
2020-06-05IPO
Leadership Team
Carlos Santos
Chief Financial Officer
Alan Bash
President, CARVYKTI
Recent News
2025-12-18
thefly.com
2025-12-09
Company data provided by crunchbase