Eli Lilly and Company · 1 month ago
TSMS Lab Sr. Principal Analytical Scientist
US, Lebanon IN
Full-time
Onsite
Senior Level, Lead/Staff
$66K/yr - $172K/yr
10+ years expEli Lilly and Company is seeking a highly experienced and innovative Senior Principal Analytical Scientist to lead critical analytical development and support activities within our Technical Services and Manufacturing Sciences (TSMS) Lab. This role will be instrumental in advancing Eli Lilly's pipeline by providing expert analytical oversight, troubleshooting complex issues, and driving the implementation of cutting-edge analytical technologies to ensure product quality and process understanding.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Serve as a subject matter expert in analytical science, providing strategic direction and technical leadership for complex analytical projects within the TSMS Lab
Lead the design and development of complex LC-MS methods for the identification, quantification, and characterization of small molecules and peptides in support of API commercial manufacturing
Independently leading deviation investigations and process optimization initiatives using analytical methodologies, especially LC/MS
Proactively identify, evaluate, and implement new analytical technologies and instrumentation to enhance capabilities, improve efficiency, and support API manufacturing
Ensure all analytical activities are conducted in accordance with cGMP, ICH, and other relevant regulatory guidelines
Collaborate effectively with cross-functional teams including process development, manufacturing, quality control, and regulatory affairs. Mentor and provide technical guidance to junior scientists and laboratory personnel
Critically analyze and interpret complex analytical data, generating comprehensive reports and presentations to communicate findings and recommendations to stakeholders
Maintain meticulous laboratory notebooks, author analytical method documentation, and technical transfer documents
Qualification
Required
Education: Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related scientific discipline with at least 10 years of relevant experience in the pharmaceutical or biotechnology industry; OR a Master's degree with at least 12 years of relevant experience; OR a Bachelor's degree with at least 15 years of relevant experience
Technical Expertise: Extensive hands-on experience and deep theoretical understanding of a broad range of analytical techniques, including chromatography (HPLC, GC, UPLC), mass spectrometry (LC-MS/MS, GC-MS), spectroscopy (UV-Vis, FTIR, Raman), and other relevant physiochemical characterization methods
Problem-Solving Skills: Demonstrated ability to independently troubleshoot complex analytical challenges, conduct OOS investigations, and implement effective solutions
Regulatory Knowledge: In-depth knowledge of cGMP, ICH guidelines, and other global regulatory requirements pertaining to analytical method development, validation, and quality control
Leadership & Mentorship: Proven ability to provide technical leadership, mentor junior scientists, and influence technical direction within a team or project
Communication Skills: Excellent written and verbal communication skills, with the ability to present complex scientific information clearly and concisely to diverse audiences
Collaboration: Strong interpersonal skills with a proven ability to collaborate effectively in a cross-functional team environment
Innovation: Demonstrated track record of identifying and implementing new analytical technologies or approaches to solve scientific problems
Benefits
Company-sponsored 401(k)
Pension
Vacation benefits
Eligibility for medical, dental, vision and prescription drug benefits
Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
Life insurance and death benefits
Certain time off and leave of absence benefits
Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Company
Eli Lilly and Company
We're a medicine company turning science into healing to make life better for people around the world.
10001+ employees
H1B Sponsorship
Eli Lilly and Company has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
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Trends of Total Sponsorships
2025 (514)
2024 (236)
2023 (167)
2022 (133)
2021 (57)
2020 (52)
Funding
Current Stage
Public CompanyTotal Funding
$6.5M2024-02-12Post Ipo Debt· $6.5M
1978-01-13IPO
Leadership Team
David Ricks
Chair, CEO
Lucas Montarce
Executive Vice President and Chief Financial Officer
Recent News
2026-01-11
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2026-01-11
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