Praxis Precision Medicines, Inc. · 1 month ago
Associate Director, Statistical Data Scientist
United States
Full-time
Remote
Lead/Staff, Director/Executive
$178K/yr - $198K/yr
8+ years expPraxis Precision Medicines is a clinical-stage biopharmaceutical company focused on developing therapies for central nervous system disorders. They are seeking an Associate Director, Statistical Data Scientist to lead the development and automation of analytical pipelines and statistical models, contributing to R/Python development while mentoring peers and ensuring regulatory readiness.
Alternative MedicineBiotechnologyHealth CareMedicalPrecision Medicine
Responsibilities
Lead the design, development, and validation of R/Python code to automate generation of analytical datasets and TLFs within a metadata-driven pipeline
Translate SAPs and metadata specifications (YAML/CSV) into executable and reproducible code
Build and validate R packages and data science tools supporting both exploratory and confirmatory analyses, ensuring full traceability and audit readiness
Implement and validate statistical models (e.g., MMRM, ANCOVA, logistic regression) using R packages such as mmrm, emmeans
Collaborate with IT to integrate data science and statistical programming workflows within Databricks and CI/CD pipelines for continuous validation and reproducibility
Collaborate across programming, biostatistics, and data standards functions to ensure dataset definitions, derivations, and metadata align with controlled standards
Conduct peer code reviews, unit testing, and automated validation; ensuring deliverables meet submission-quality and reproducibility standards
Mentor and guide team members in best practices for programming, validation, and automation
Qualification
Required
Bachelor's or Master's degree in Statistics, Biostatistics, Data Science, or a related field with 8+ years of statistical programming experience in the pharmaceutical/biotech industry including hands-on experience with R and/or Python
Proven experience preparing or supporting R-based regulatory submissions (e.g., R package validation, R-based analysis delivery, or submission readiness)
Strong understanding of CDISC ADaM and SDTM data structures, and their use in analytical workflows
Experience developing and validating reusable R/Python libraries and functions
Proficiency with Git, Bitbucket, and CI/CD automation pipelines
Working knowledge of GxP and Part 11 compliance
Excellent documentation and validation practices
Collaborative and proactive mindset; able to operate independently in a small, agile team
Preferred
Familiarity with YAML/JSON configuration and metadata-driven programming workflows
Prior experience migrating from SAS to R/Python environments
Knowledge of R validation frameworks (e.g., risk-based testing, reproducibility documentation)
Experience with exploratory analytics or visualization in R or Python within a regulated framework strongly preferred
Benefits
99% of the premium paid for medical, dental and vision plans.
Company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage.
We match dollar-for-dollar up to 6% on eligible 401(k) contributions.
Long-term stock incentives and ESPP.
Discretionary quarterly bonus.
Extremely flexible wellness benefit.
Generous PTO.
Paid holidays and company-wide shutdowns.
Company
Praxis Precision Medicines, Inc.
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.
51-200 employees
H1B Sponsorship
Praxis Precision Medicines, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.67BKey Investors
Eventide
2026-01-06Post Ipo Equity· $575M
2025-10-16Post Ipo Equity· $525M
2024-03-28Post Ipo Equity· $200M
Leadership Team
Marcio Souza
President and CEO
Tim Kelly
Chief Financial Officer
Recent News
2026-01-07
2026-01-07
Company data provided by crunchbase