Baylor College of Medicine · 21 hours ago
Staff Scientist - Stem Cells
Houston, TX
Full-time
Onsite
Senior Level, Lead/Staff
$65K/yr - $85K/yr
3+ years expBaylor College of Medicine is a leading research institution, and they are seeking an experienced Staff Scientist to lead the lab's core iPSC and genome engineering operations. This role involves designing and executing CRISPR/Cas9 editing strategies and optimizing differentiation protocols to create various neural cell types.
EducationHigher EducationPharmaceutical
Responsibilities
Lead mechanistic studies of human iPSC models of neurodevelopmental and neurodegenerative disorders, together with PI and other lab members
Design, execute, and validate CRISPR/Cas9 genome editing experiments (e.g., knock-outs, knock-ins, single-nucleotide variants) in human iPSCs and perform downstream QC
Perform advanced cellular and molecular analyses (immunocytochemistry, confocal microscopy, qPCR, Western blot)
Maintain highly detailed and accurate records of all experimental procedures and results in an electronic lab notebook
Analyze and interpret data, prepare figures, and present findings clearly to the Principal Investigator and lab group
Train and mentor graduate students, post-doctoral fellows, and research technicians in advanced stem cell culture and genome editing techniques
Assist with lab management duties, including reagent ordering, stock maintenance, and ensuring protocol compliance
Assist in grant writing
Perform other job related duties as assigned
Qualification
Required
Doctoral Degree. Experience may not be substituted in lieu of degree
Three years of post doctoral research experience
Extensive hands-on experience with human iPSC culture, maintenance, and quality control
Demonstrated expertise in designing and successfully executing CRISPR/Cas9 genome editing projects in iPSCs
Proven track record in developing and troubleshooting protocols for neural differentiation and/or 3D organoid culture
Proficiency in standard molecular biology techniques (cloning, PCR, qPCR) and cellular analysis (immunofluorescence, confocal microscopy, flow cytometry)
Strong analytical skills and experience with relevant data analysis software (e.g., ImageJ, GraphPad Prism)
Excellent organizational skills, attention to detail, and ability to manage multiple projects simultaneously
Preferred
Prior experience supervising or training junior research staff
Company
Baylor College of Medicine
Baylor College of Medicine, located in the Texas Medical Center, is a health sciences university located in Houston, Texas
5001-10000 employees
H1B Sponsorship
Baylor College of Medicine has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (252)
2024 (208)
2023 (164)
2022 (196)
2021 (126)
2020 (136)
Funding
Current Stage
Late StageTotal Funding
$10.85MKey Investors
National Human Genome Research InstituteNational Heart, Lung and Blood InstituteCancer Prevention and Research Institute of Texas
2024-12-05Grant· $3.5M
2024-09-26Grant
2024-09-19Grant
Leadership Team
Paul Klotman
President, CEO and Executive Dean
Peggy Smith
Professir and CEO. Teen Health Clinics
Recent News
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2025-12-16
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