Alnylam Pharmaceuticals · 1 day ago
Principal Associate Scientist, Bioanalytical Sciences
Cambridge, MA
Full-time
Onsite
Senior Level, Lead/Staff
$97K/yr - $137K/yr
6+ years expAlnylam Pharmaceuticals is a leader in RNAi therapeutics, seeking a highly motivated Principal Associate Scientist to join their Bioanalytical Sciences group. This role focuses on molecular PCR-based assays to support RNAi therapeutic programs from discovery to the clinic, requiring strong molecular biology skills and the ability to collaborate with multiple project teams.
BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Hiring Manager
Jeannine Ripley
Responsibilities
Implement gene expression assays to inform target engagement in biological matrices using techniques such as RT-qPCR or dPCR
Evaluate and implement fit-for-purpose automated RNA extraction methods to improve consistency and performance of gene expression assays
In support of program priorities, perform non-GLP sample analysis for emerging and established tissues to support all of Alnylam’s RNAi therapeutic development from early to late stages
Design, troubleshoot and interpret experiments
Help implement and maintain appropriate procedures and controls to ensure consistent assay performance and reproducible data
Maintain meticulous laboratory notebooks, perform data analysis and QC, and communicate results to matrixed teams to support program advancement
Collaborate with team members to expand capabilities and improve workflows for molecular analysis and data reporting
Qualification
Required
A Master's degree (6+ years of relevant industry experience) or Bachelor's degree (8+ years of relevant industry experience) in molecular biology, biochemistry, chemistry, or relevant field
Excellent lab technique and previous experience to perform PCR-based molecular assays, and ability to work independently
Has experience with Excel, Word, PowerPoint, and other analytical software (e.g. GraphPad Prism, QuantStudio)
Detail-oriented and organized with the ability to thrive in a team environment and be comfortable working on and prioritizing multiple projects
Has strong interpersonal skills to enable collaboration with cross-functional teams
Possesses excellent verbal and written communication skills
Preferred
Experience with biological matrices across preclinical species is strongly preferred
A quick learner with proven ability to perform in a fast paced working environment
Benefits
Comprehensive benefits including medical, dental, and vision coverage
Life and disability insurance
A lifestyle reimbursement program
Flexible spending and health savings accounts
A 401(k) with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
2025-12-22
2025-12-20
Company data provided by crunchbase