Principal Scientist-Drug Discovery jobs in United States
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Creative Biostructure ยท 2 months ago

Principal Scientist-Drug Discovery

Creative Biostructure is committed to accelerating the preclinical discovery and development of innovative drugs through structural insights. They are seeking a principal scientist specialized in innovative drug discovery to lead efforts across research functions to design and develop therapeutic proteins/antibodies or small-molecule drugs.

BiopharmaBiotechnologyHealth CarePharmaceutical

Responsibilities

Establish and manage a team of interdisciplinary scientists
Contribute to the effort for developing a structure-guided innovative drug discovery platform
Lead and supervise structure-based preclinical drug R&D programs of biologics or small-molecule drugs
Support patent applications and registration
Write technical documents, such as standard operating procedures (SOP), protocols, and project reports

Qualification

Structure-guided drug discoveryTherapeutic proteins/antibodiesSmall-molecule drugsPreclinical drug discoveryLeadership skillsTechnical writingCollaboration skills

Required

Ph.D. in Biochemistry and Molecular Biology, Biophysics, Structural Biology, Cell Biology, Medicinal Chemistry, Immunology, or related fields
A minimum of 5 years of industry experience in structure-guided drug discovery (therapeutic proteins/antibodies or small-molecule drugs)
Excellent record of successful research, including papers published in peer-reviewed journals
Hands-on experience in preclinical drug discovery project including Hit identification, Hit-to-Lead, Lead optimization and preclinical development
Strong leadership and managerial skills to establish and manage successful relationships with internal and external collaborators

Company

Creative Biostructure

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Creative Biostructure offers x-ray crystallography, microscopy and structural biology services for the pharmaceutical industries.