Ionis Pharmaceuticals, Inc. · 1 month ago
Postdoctoral Fellow, Immunology
Ionis Pharmaceuticals, Inc. is a pioneer in RNA-targeted medicines, dedicated to discovering medical breakthroughs for serious diseases. The Postdoctoral Fellow will contribute to advancing targeted RNA-therapeutics delivery to immune cells, exploring receptor-based delivery strategies and validating them through various analytical approaches.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Identify and prioritize cell-surface receptors relevant to immune-cell biology, applying scientific creativity and critical thinking to advance delivery strategies
Validate receptor expression and function using advanced analytical approaches, including flow cytometry, single-cell profiling, and RNA-seq
Design and execute in vitro and in vivo studies to evaluate target knockdown, delivery efficiency, and cell-type specificity, exercising sound judgment within established procedures
Analyze and interpret complex datasets to guide decision-making, review key technical factors, and shape project strategy
Document experimental results and communicate clear, concise findings through regular internal presentations, writing manuscripts for scientific publications, and contributions to posters
Collaborate effectively with cross-functional teams and external partners, building alignment around technical decisions and contributing to collective problem-solving
Contribute to innovation and intellectual property development through rigorous experimentation and documentation
Demonstrate professionalism and uphold the company’s culture, core principles, and collaborative working norms
Qualification
Required
Ph.D. in Immunology, Molecular Biology, Cell Biology, or related fields with 0-3 years of postgraduate training
Familiarity with flow cytometry, including panel design and data analysis
Experience with cell culture techniques, including primary immune cell isolation and maintenance
In vivo study experience or willingness to learn
Experience with molecular biology methods (e.g., RNA analysis, qPCR, siRNA/ASO delivery)
Strong background in immunology and lymphocyte biology is a plus
Ability to analyze large datasets (e.g., scRNA-seq, transcriptomics) and interpret receptor expression profiles is a plus
Excellent problem-solving skills and ability to design experiments independently
Strong written and verbal communication skills for publication and presentation
Required to be full-time onsite at Carlsbad, CA
Benefits
Ionis offers an excellent benefits package!
Company
Ionis Pharmaceuticals, Inc.
For three decades, Ionis has invented medicines that bring better futures to people with serious diseases.
H1B Sponsorship
Ionis Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (5)
2023 (3)
2022 (5)
2021 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$2.45B2025-11-13Post Ipo Debt· $700M
2024-09-09Post Ipo Equity· $500.3M
2023-06-06Post Ipo Debt· $500M
Leadership Team
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