BBOT ยท 3 days ago
Senior Scientist/Principal Scientist, Pharmacology
South San Francisco, CA
Full-time
Onsite
Senior Level, Lead/Staff
$138K/yr - $178K/yr
3+ years expBBOT is a clinical-stage biopharmaceutical company focused on developing novel small molecule therapeutics for cancer treatment. They are seeking a Senior Scientist/Principal Scientist with extensive in vivo pharmacology experience to lead pharmacology strategies and collaborate with cross-functional teams in the oncology drug discovery process.
Biotechnology
Responsibilities
Drive and implement the pharmacology strategy for small molecule therapeutics for oncology indications through lead optimization, development candidate selection, IND-enabling, and clinical development stages
Serve as the pharmacology functional team leader for one or more programs and collaborate with cross-functional program teams and leaders to support molecule advancement
Lead in vivo (model development, tolerability, PK/PD, and efficacy) and ex vivo (target and mechanism engagement) studies to assess the inhibition or activation of oncology targets with novel small molecule therapeutics
Manage and provide strategic and technical leadership to a team of research associates
Write reports and regulatory documents
Lead academic collaborations with academic researchers and KOLs
Manage CROs to deliver high quality data in a timely manner
Qualification
Required
A highly motivated, committed individual with good organizational skills and a demonstrated commitment to quality, attention to detail, and team player mentality
Ph.D. in a biology-related discipline with postdoctoral fellowship and at least 3 years of industry experience is required
Accomplished oncology scientist as evidenced by publication record
Broad experience with in vivo CDX, PDX, and syngeneic models
Experience managing scientist and research associate level personnel and demonstrated ability to effectively train, manage, and mentor associates on proper in vivo protocols and procedures
Experience managing diverse and multiple CROs
Strong written and oral communication skills
Preferred
Experience writing pharmacology section of IND a plus
Benefits
Annual bonus
Stock-based long-term incentives
Medical, dental, and vision benefits
Retirement
Wellness stipend
Flexible time off
Company
BBOT
BBOT (BridgeBio Oncology Therapeutics) is a clinical-stage biopharmaceutical company advancing a next generation pipeline of novel small molecule therapeutics targeting RAS and PI3K malignancies.
51-200 employees
H1B Sponsorship
BBOT has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (1)
Funding
Current Stage
Growth StageCompany data provided by crunchbase