MacroGenics, Inc. · 1 month ago
Associate Scientist II/Scientist I (Biologics Expression and Purification)
Rockville, MD
Full-time
Onsite
Entry, Mid Level
$67K/yr - $102K/yr
2+ years expMacroGenics, Inc. is a leader in the discovery and development of innovative medicines utilizing antibody-based technologies. They are seeking an Associate Scientist II/Scientist I to support their Biologics discovery pipeline by expressing and purifying proteins in mammalian cells. The role involves cell culture, protein purification, and data analysis to contribute to drug discovery efforts.
BiotechnologyHealth CareManufacturing
Responsibilities
Culture of mammalian cells in suspension following aseptic techniques and cell-line specific protocols
Transient transfection of cell lines or expansion of stable cell pools, from 3 ml – 10 L scale, to express proteins of interest. Monitor and optimize culture conditions to maximize protein quality and expression
Protein purification from milligram to gram scale using semi-automated FPLC systems
Analytical characterization of purified proteins to support research projects for drug discovery
Collect, analyze, and summarize experimental data in electronic lab notebook for archiving and sharing
Maintain lab and lab equipment in optimal functioning condition. Report any problems to supervisor
Qualification
Required
Bachelor's degree in Biology or Biochemistry or a related field of study with a minimum of 2 years of bench-related experience for Associate Scientist II
Bachelor's degree in Biology or Biochemistry or a related field of study with a minimum of 3 years of bench-related experience for Scientist I
Master's degree in Biology or Biochemistry or a related field of study with a minimum of 1 year of bench-related experience, strongly preferred
Experience with mammalian cell culture, transfections, maintaining cell lines, etc. with meticulous sterile technique and lab practices
Experience with recombinant protein purification and analytical characterization (CE or SDS-PAGE, SEC)
Experience with experimental design and execution with minimal supervision
Experience with standard lab software for data analysis (MS Excel, Prism, etc.)
Good organizational skills and ability to multi-task
Good verbal and written communication skills
Demonstrated ability to work in a collaborative environment with other team members
Willingness to work on occasional weekends
Preferred
Experience with antibody purification using automated FPLC system
Experience with quantitative assays (BLI Octet, ELISA, etc.)
Benefits
Medical / dental / vision / prescription coverage
Employee wellness resources
401(k) plan with employer match
Access to an Employee Stock Purchase Plan, (ESPP)
Paid time off & paid parental leave benefits
Disability benefits
Company
MacroGenics, Inc.
MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies.
201-500 employees
H1B Sponsorship
MacroGenics, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (4)
2022 (1)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$275.92MKey Investors
National Institutes of HealthNextech VentureVentures West
2019-02-12Post Ipo Equity· $110M
2013-10-10IPO
2011-01-31Private Equity· $12.02M
Leadership Team
Eric Risser
Chief Executive Officer
Leroy Hood
Co-Founder
Recent News
2025-12-11
2025-11-26
MacroGenics, Inc.
2025-11-13
Company data provided by crunchbase