St. Jude Children's Research Hospital · 1 week ago
NMR Senior Scientist in Blue Sky Protein Kinases
Memphis, TN
Full-time
Onsite
Mid, Senior Level
$104K/yr - $186K/yr
5+ years expSt. Jude Children's Research Hospital is a leading pediatric research institution dedicated to advancing cures and treatments for children. They are seeking an experienced NMR spectroscopist for the Blue Sky Initiative, focusing on studying large protein kinases and their dynamics using advanced NMR techniques.
BiotechnologyCharityHealth CareHealth DiagnosticsHospitalMedicalNon Profit
Responsibilities
Conduct NMR experiments/projects independently under the overall direction of supervisor
Manage construct design, NMR data collection, chemical shift assignment, solution structure determination, and dynamics studies independently
Structure calculations and refinement using solution state NMR data
Analysis of CEST relaxation profiles
Critically evaluate viability of kinase for dynamics and/or structural studies
Work closely with team specialists to interpret data and formulate hypothesis that advance the research goals
Train, assist and oversee the work of junior colleagues in all aspects of NMR- related projects
Independently troubleshoot, solve difficult problems, and propose solutions related to research project design and execution
Work efficiently and effectively in a collaborative and multidisciplinary team environment in full accordance with St. Jude institutional values
Qualification
Required
Extensive experience in applying NMR techniques in characterization of the structure and dynamics of large proteins, including backbone and methyl assignment methodologies
Experience in using both automated and manual methods for NMR chemical shift assignment
Experience in performing characterization of protein dynamics using CEST
Proficient in NMR data processing
Experienced in NMR structure calculation and refinement
Highly motivated and detail oriented with excellent communications skills
Excellent organizational skills, with an ability to embrace change and multi-task in an extremely fast-paced environment
Bachelor's degree in relevant scientific area is required
Ten (10) years relevant work experience is required with a Bachelor's degree
Eight (8) years of relevant work experience is required with a Master's degree
Five (5) years of relevant work experience is required with a PhD
Preferred
Understand and interpret a variety multidisciplinary biochemical/biophysical data
Proficiency in using a variety of NMR processing and analysis software including nmrPipe, nmr-fam Sparky/Poky, Bruker TopSpin, and CYANA
Proficient in Alphafold, Molecular Dynamics, and structure refinement techniques such as Amber, CNS etc
Experiences in assignment of highly deuterated methyl labeled proteins using MAGIC and other algorithms
Benefits
Medical & Prescription Drug Plans
Dental Plan
Vision Plan
Financial Security
Retirement Plan
Living Well - Employee Wellness Program
Time Off Programs
Educational Benefits
Family Friendly Benefits
Benefits Unique to St. Jude
Company
St. Jude Children's Research Hospital
St.
5001-10000 employees
H1B Sponsorship
St. Jude Children's Research Hospital has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (370)
2024 (316)
2023 (309)
2022 (255)
2021 (251)
2020 (201)
Funding
Current Stage
Late StageTotal Funding
$62.4MKey Investors
Kia MotorsKBR Charity Golf TournamentHyundai Hope On Wheels
2025-05-12Grant· $1.5M
2024-10-28Grant
2024-08-28Grant· $0.4M
Leadership Team
Judy A. Habib
Chair, Board of Directors
Recent News
Genetic Engineering News
2026-01-06
2026-01-06
Medical Xpress - latest medical and health news stories
2026-01-05
Company data provided by crunchbase