OPEN Health · 1 week ago
Associate Scientist/Scientist, Psychometrics, Patient Centered Outcomes
United States
Full-time
Remote
Mid, Senior LevelOPEN Health is a global organization committed to improving patient outcomes worldwide. The Associate Scientist/Scientist in Psychometrics will lead and support the design and execution of quantitative studies, focusing on measurement development and validation in health economics and outcomes research. This role involves collaboration with clients and stakeholders to ensure effective project execution and communication of clinical outcome assessments.
ConsultingDatabaseHealth CareMedical
Responsibilities
Designing, analyzing, and reporting of both interventional and non-interventional studies evaluating clinical outcomes assessments (COAs): patient-reported outcome (PRO), observer-reported outcome (ObsRO), clinician-reported outcome (ClinRO), and performance outcome (PerfO) assessments
Serving as an expert analyst to provide input regarding COAs
Leading programming and interpretation of advanced psychometric analysis, including:
Psychometric analyses
+ Modern psychometric methods, including factor analysis, item response theory, tests of local dependence, differential item/test functioning, scoring evaluation
+ Classical test theory, including internal consistency, test-retest reliability, responsiveness
+ Meaningful score difference/range estimation using current regulatory-recommended methods
Linear/generalized linear mixed models
Latent variable models
Survival models (including mixture and joint models)
Advising on or supporting the development of COA-focused strategies for client interactions/submissions with health authorities including regulatory agencies (e.g., FDA, EMA) and HTA bodies
Interacting with federal regulators at the US Food and Drug Administration (FDA) and European Medicines Agency (EMA), along with occasional interaction with other international regulators
Developing study documents such as study proposals, protocols, statistical or psychometric analysis plans, COA dossiers, technical reports, and study presentations
Reporting, drafting and finalizing technical reports, regulatory briefing packages, and manuscripts
Building client relationships, which involves communication with both federal grant and pharmaceutical industry funding sponsors
Qualification
Required
Master's degree or doctoral-level degree (PhD, MD, PharmD) in biostatistics, psychometrics, quantitative psychology, educational measurement, or a related field
Knowledge of advanced psychometric methods including factor analysis and item response theory/Rasch analysis
Experience performing modern psychometric methods and classical test theory analyses in statistical software
Fluency in at least one primary programming language (R strongly preferred)
Experience in a comparable industry, ideally from research organization or pharma environment
Strong attention to detail and superior communication skills (both written and verbal)
Strong analysis interpretation and organization skills, including the ability to prepare and present relevant summaries of complex materials to non-analytic audiences
Comfort in a client-facing role
Proactive, efficient, and adaptable with the ability to learn quickly
Demonstrated collaboration and communication skills
Preferred
Experience mentoring, guiding, and providing hands-on support to less-experienced analysts is desirable
Experience in clinical outcomes assessments (COAs, including, but not limited to PROs)
Experience with submissions to regulatory agencies is desirable
Benefits
Competitive pay, generous paid vacation, holidays and more, across all our locations
Ongoing training and development opportunities which foster and shape your individual career path
An active and growing commitment to bettering the communities our employees call home through our Corporate Social Responsibility program
The opportunity to thrive in a global, collaborative environment while working every day to improve health outcomes and patient wellbeing
Diverse, inclusive culture that encourages you to bring your whole self to work
Company
OPEN Health
OPEN Health provides medical communications, omni, HEOR, and market access services.
Founded in 2011
1001-5000 employees
H1B Sponsorship
OPEN Health has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (1)
2022 (2)
2021 (5)
Funding
Current Stage
Late StageTotal Funding
$1.3MKey Investors
YZR Capital
2023-12-31Pre Seed· $1.3M
Leadership Team
Annemarie Clegg
Chief Medical Officer
Recent News
2025-09-15
2025-08-27
Company data provided by crunchbase