Moderna · 1 day ago
GxP Endpoint Engineer
Cambridge, MA
Full-time
Onsite
Senior Level
$131K/yr - $209K/yr
6+ years expModerna is a leading mRNA technology company focused on transforming medicine. The GxP Endpoint Engineer will manage the SCCM environment to support GxP operations, ensuring compliance with QA guidance and maintaining a validated infrastructure for operating system deployments and application distribution.
BiotechnologyGeneticsHealth CareMedicalPharmaceuticalTherapeutics
No H1B
U.S. Citizen Only
Responsibilities
Own and manage the SCCM GxP environment, ensuring all configurations, task sequences, and deployments comply with QA guidance and validation standards
Design, document, and maintain standard operating procedures (SOPs) and configuration baselines specific to GxP systems
Implement and monitor strict QC processes for all deployments, including peer review, QA validation, and change control sign-off prior to production release
Oversee all operating system deployments and in-place upgrades (IPU) for validated systems, ensuring consistent execution under GxP change control
Manage patching cycles, including Microsoft and third-party updates, coordinating with QA, GxP Support, and Application Owners to plan, validate, and document each phase
Create and maintain deployment and compliance reports, providing transparency to QA and management on patch and configuration status across the GxP fleet
Collaborate with Application Owners and GxP Support teams to coordinate deployments, validate installations, and resolve environment-specific issues
Develop and publish Knowledge Base (KB) articles and operational guides for support teams and end users related to SCCM processes, patching, and imaging
Serve as the escalation point for packaging, deployment, and compliance failures impacting GxP systems
Partner with QA to participate in audits, provide system validation evidence, and ensure documentation accuracy across all controlled activities
Contribute to the ongoing evolution of how SCCM operates in Moderna’s validated environment, helping to design scalable, compliant frameworks for automation and reporting
Qualification
Required
6+ years of experience in SCCM/MECM administration, including task sequences, OSD, collections, compliance baselines, and application deployments
Proven experience managing systems in regulated (GxP, GMP, or validated) environments, adhering to QA and change control processes
Strong understanding of QA, QC, and validation principles within endpoint management
Experience performing in-place upgrades (IPUs), PXE imaging, and patch management in controlled environments
Hands-on experience with third-party patching tools and their integration with SCCM
Familiarity with ServiceNow for change control, approval workflows, and incident tracking
Ability to produce comprehensive documentation, SOPs, and KBs aligned with GxP validation standards
Strong collaboration skills to engage with QA, Application Owners, and Support teams on validation, testing, and incident management
Preferred
Analytical mindset and attention to detail to ensure every configuration and deployment meets compliance and performance expectations
Bachelor's degree in Information Technology, Computer Science, or a related technical discipline
Experience with co-managed SCCM + Intune environments in validated systems
Familiarity with JAMF Pro for cross-platform GxP compliance awareness
Knowledge of GAMP 5 validation principles or equivalent regulated system frameworks
Prior experience generating QA audit documentation or participating in validation testing for endpoint systems
Understanding of Windows OS lifecycle management and modern endpoint management best practices
Certifications such as Microsoft Endpoint Manager, ITIL, or CompTIA Security+
A proactive, methodical approach to process improvement and compliance-driven automation
Benefits
Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
Family planning benefits, including fertility, adoption, and surrogacy support
Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
Savings and investment opportunities to help you plan for the future
Location-specific perks and extras
Company
Moderna
Moderna Therapeutics is a biotechnology company that specializes in vaccines and drug development.
1001-5000 employees
Funding
Current Stage
Public CompanyTotal Funding
$4.56BKey Investors
Coalition for Epidemic Preparedness InnovationsAres ManagementU.S. Department of Health & Human Services
2025-12-18Grant· $54.3M
2025-11-20Post Ipo Debt· $600M
2024-07-02Grant· $176M
Leadership Team
Stephane Bancel
Founding CEO
Kenneth Chien
Co-Founder
Recent News
2026-01-07
Company data provided by crunchbase