Syngenta · 1 month ago
Protein Structure Search & Design Intern
Durham, NC
Internship
Onsite
InternSyngenta Seeds is a global leader in developing high-quality seeds to improve crop yields. The Protein Structure Search & Design Intern will apply structural bioinformatics methods to discover novel proteins and develop computational workflows for protein candidate identification and ranking.
AgricultureFarming
Responsibilities
Apply structural bioinformatics methods to discover novel proteins
Develop computational workflows that integrate sequence and structure-based search algorithms to identify and rank protein candidates
Implement protein structure-based search workflows using tools like FoldSeek, ESMFold, and Boltz
Perform structural analysis and annotation of protein candidates
Develop Python/Bash scripts for data processing and visualization
Document workflows, create user guides, and present findings to cross-functional teams
Collaborate with other scientists to refine research strategies based on biological insights
Share results and learnings at team meetings and educate team members on workflows and results
Qualification
Required
Current MS or PhD student in Bioinformatics, Computational Biology, Structural Biology, or related field
Proficiency in Python and/or R for bioinformatics (PyRosetta a plus)
Basic understanding of protein structure concepts (protein domains, structural alignment)
Familiarity of protein structure prediction methods (AlphaFold2, ESMFold, Boltz)
Familiarity with protein structure visualization (PyMOL or ChimeraX)
Experience with Linux/Unix command-line environments
Knowledge of sequence analysis tools (BLAST, alignment methods)
Ability to work with large datasets and implement reproducible computational workflows
Strong problem-solving skills and attention to detail
Effective written and verbal communication skills
Preferred
Experience with protein structure comparison tools (TM-align, FoldSeek)
Experience with protein function prediction tools (InterProScan or ESM-based methods)
Knowledge of protein databases (PDB, UniProt, AlphaFoldDB, ESM Metagenomic Atlas)
Experience with HPC or cloud computing
Self-motivated with ability to work independently and collaboratively
Enthusiasm for learning new computational methods and tools
Experience presenting technical work to diverse audiences
Company
Syngenta
Syngenta is an agriculture company provides products and solutions to help farmers achieve global food security for a growing population. It is a sub-organization of Syngenta Group.
Founded in 2000
10001+ employees
H1B Sponsorship
Syngenta has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$2.97MKey Investors
Scottish Enterprise
2025-05-29Grant· $2.97M
2016-02-04Acquired
2000-11-13IPO
Leadership Team
Fabio Neufeld
Head of Financial Solutions
Jean Albert
Global Head Crop Protection R&D Technology Acquisition & Collaboration Management
Recent News
FoodHack Weekly
2025-12-06
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