Staff Software Engineer – Data Team (Menlo Park, CA ) #4433 jobs in United States
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GRAIL · 4 hours ago

Staff Software Engineer – Data Team (Menlo Park, CA ) #4433

GRAIL is a healthcare company pioneering new technologies to advance early cancer detection. They are seeking a Staff Software Engineer for the Data Team to design and implement software systems that manage GRAIL’s end-to-end data lifecycle, supporting clinical research and operational decision-making.

BiotechnologyHealth CareHealth DiagnosticsMedicalMedical Device
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H1B Sponsor Likelynote

Responsibilities

Design and implement software systems that turn raw clinical, lab, and operational data into reliable, analysis-ready datasets
Partner with scientists, clinicians, lab operations, and data teams to understand data generation, transformation, and usage needs
Develop services, libraries, data models, and workflow components that enforce data integrity, access control, and compliance by design
Navigate complex data requirements such as schema evolution, blinding, consent, and privacy compliance
Collaborate on cross-functional initiatives involving data quality, testing strategy, monitoring, and operational excellence
Lead software engineering efforts for long-lived systems that must evolve alongside active clinical and research programs
Mentor engineers and collaborate with scientists to ensure software decisions support both technical and scientific outcomes
Contribute to documentation, onboarding materials, and processes that support cross-functional adoption and data literacy across teams
Participate in incident response or investigation processes related to data quality or availability issues in production systems

Qualification

Production-grade software systemsData modelingAPI designGoPythonData-intensive software systemsRegulated data environmentsLaboratory data managementMentoring engineersCollaboration with scientistsDocumentation contribution

Required

7+ years of experience building production-grade software systems
Strong software engineering fundamentals, including system design, data modeling, API design, and writing well-tested production code
Experience building and operating data-intensive software systems, not just declarative pipelines or SQL-only workflows
Proficiency in Go or Python (or similar general-purpose language)
Experience with data modeling, validation, and transforming real-world data into usable formats
BS in Computer Science, Engineering or Bioinformatics, or a related field, or equivalent practical experience

Preferred

2+ years experience working in regulated or clinical data environments (e.g., HIPAA, CLIA, GCP, FDA compliance)
Direct experience working with or supporting scientific teams (e.g., bioinformatics, wet lab, clinical research)
Experience designing systems that manage laboratory or bioinformatics data (e.g., LIMS, sequencing pipelines, assay metadata)
Familiarity with GxP practices and regulatory reporting requirements in clinical studies is a plus
Prior experience working in biotech, diagnostics, or life sciences companies
Experience supporting sample tracking, structured scientific data pipelines, or cross-functional data lifecycle management
Experience designing systems with data sequestration, permissioning, or privacy controls
Experience writing or contributing to software libraries, shared tooling, or reusable components used by other teams
Advanced degree (MS or PhD) in computer science, engineering, bioinformatics or a related discipline

Benefits

Flexible time-off or vacation
A 401(k) retirement plan with employer match
Medical, dental, and vision coverage
Carefully selected mindfulness programs

Company

Grail is a healthcare company that develops pan-cancer screening tests designed to detect cancers at an early stage.

H1B Sponsorship

GRAIL has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (21)
2024 (26)
2023 (23)
2022 (46)
2021 (25)
2020 (9)

Funding

Current Stage
Public Company
Total Funding
$2.44B
Key Investors
ARCH Venture PartnersIllumina
2025-10-20Post Ipo Equity· $325M
2025-10-16Post Ipo Equity· $110M
2024-06-13IPO

Leadership Team

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Satnam Alag
Senior Vice President Software Engineering and Chief Security Officer
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Joshua J. Ofman
President
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Company data provided by crunchbase